VACWR034 Antibody

Code CSB-PA323585ZA01VAI
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Product Details

Full Product Name Rabbit anti-Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR)) VACWR034 Polyclonal antibody
Uniprot No. P18378
Target Names VACWR034
Alternative Names VACWR034 antibody; K2L antibody; K3L antibody; Protein K3 antibody; Protein K2 antibody
Raised in Rabbit
Species Reactivity Vaccinia virus
Immunogen Recombinant Vaccinia virus VACWR034 protein
Immunogen Species Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables ① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee ① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time Made-to-order (12-14 weeks)

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Target Background

Function
(From Uniprot)
Viral mimic of eIF-2-alpha that acts as a pseudosubstrate for EIF2AK2/PKR kinase. Inhibits therefore eIF-2-alpha phosphorylation by host EIF2AK2/PKR kinase and prevents protein synthesis shutoff.
Gene References into Functions
  1. effects of the PKR mutations on pseudosubstrate vs. substrate interactions reflect differences between the rigid K3L protein and the plastic nature of eIF2alpha around the Ser-51 phosphorylation site. PMID: 18971339
Protein Families Poxviridae K3 protein family
Database Links

KEGG: vg:3707649

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