prgI Antibody

Code CSB-PA336905ZA01SXB
Size US$299
Image
  • Western Blot
    Positive WB detected in Recombinant protein
    All lanes: prgI antibody at 1:2000
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 24.9 kDa
    Observed band size: 30 kDa
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Product Details

Full Product Name
Rabbit anti-Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) prgI Polyclonal antibody
Uniprot No.
Target Names
prgI
Alternative Names
prgI antibody; STM2873 antibody; Protein PrgI antibody
Raised in
Rabbit
Species Reactivity
Salmonella typhimurium
Immunogen
Recombinant Salmonella typhimurium Protein prgI (prgI) (1-80AA)
Immunogen Species
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Protein A/G
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Description

The prgI antibody is meticulously crafted by immunizing a rabbit with recombinant Salmonella typhimurium prgI (1-80aa), inducing the rabbit's B lymphocytes to produce tailored IgG antibodies. This polyclonal prgI antibody is then meticulously purified from the rabbit's serum utilizing protein A/G methods. This antibody is suitable for the detection of Salmonella typhimurium prgI protein in ELISA and WB assays.

The Salmonella typhimurium PrgI protein is a crucial component of the type III secretion system (T3SS) needle complex, which is used by the bacterium to inject virulence factors into host cells. PrgI forms the needle structure itself and acts as a conduit for the delivery of bacterial proteins into host cells during infection. This process allows Salmonella to manipulate the host cell's machinery for its own benefit, facilitating its pathogenicity and survival within the host.

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Target Background

Function
Required for invasion of epithelial cells.
Gene References into Functions
  1. analysis of structural and functional similarity between the bacterial type III secretion system needle protein PrgI and the eukaryotic apoptosis Bcl-2 proteins PMID: 19823588
  2. Thermodynamic characterization of the structural stability of the PrgI protein. PMID: 16501225
  3. analysis of electrostatic surfaces of the type III secretion needle proteins PrgI, BsaL, and MxiH PMID: 17617421
Protein Families
MxiH/PrgI/YscF family
Database Links

KEGG: stm:STM2873

STRING: 99287.STM2873

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