psaA Antibody

Rare Species
Code CSB-PA337054ZA01FMW
Size US$299
Image
  • Western Blot
    Positive WB detected in: recombinant protein
    All lanes: psaA Antibody at 1:1000
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 42 kDa
    Observed band size: 42 kDa
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Product Details

Uniprot No.
Target Names
psaA
Alternative Names
Manganese ABC transporter substrate-binding lipoprotein (Pneumococcal surface adhesin A), psaA, papA
Species Reactivity
Streptococcus pneumoniae
Immunogen
Recombinant Streptococcus pneumoniae psaA protein (21-310aa)
Immunogen Species
Streptococcus pneumoniae
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Affinity-chromatography
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Description

To create the psaA polyclonal antibody, a recombinant Streptococcus pneumoniae psaA protein fragment (comprising amino acids 21 to 310) serves as the chosen immunogen. This fragment is introduced into a rabbit for immunization, prompting the development of an antibody response. Subsequently, serum is obtained from the rabbit and purified through affinity chromatography to obtain polyclonal antibodies. Rigorous validation is conducted to confirm the psaA antibody's specificity for Streptococcus pneumoniae psaA protein through ELISA and WB assays.

Pneumococcal surface adhesin A (psaA) is a lipoprotein component of the Mn2+ transporter, found on the surface of all known serotypes of Streptococcus pneumoniae. It is an adhesin that plays a crucial role in the attachment of pneumococci to host cells and contributes to their virulence. psaA is also immunogenic and natural colonization of the nasopharynx by pneumococci leads to an increase in antibody production against PsaA.

Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Part of an ABC transporter complex involved in manganese import.
Subcellular Location
Cell membrane; Lipid-anchor.
Protein Families
Bacterial solute-binding protein 9 family, Lipoprotein receptor antigen (Lrai) subfamily
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