Recombinant Rat Guanylate cyclase soluble subunit beta-1 (Gucy1b3)

1. The effect of glucagon-like peptide-2 on the expression of the alpha1, alpha2, and beta1 subunits of soluble guanylyl cyclase, was studied. PMID: 22806360
2. soluble GCbeta1 plays an important role in the restructuring of the adherens junction in the testis [sGCbeta1] PMID: 16547975
3. Identify hydrogen peroxide as an endogenous mediator contributing to the regulation of vascular tone and point to a key role of HuR in sGCbeta1 mRNA stabilization. PMID: 21164076
4. Soluble guanylate cyclase is activated by binding of carbon monoxide and YC-1. PMID: 20353168
5. soluble guanylate cyclase beta 1 expression in the vasculature of rat skeletal muscle PMID: 20009348
6. mapping of heme-binding domain PMID: 11688978
7. treatment of rat brain astrocytes with betaA decreases their capacity to accumulate cyclic GMP (cGMP) in response to NO as a result of a decreased expression of soluble guanylyl cyclase alpha-1 and beta-1 subunits at the protein and mRNA levels. PMID: 12127152
8. Expression of sGC beta 1 subunit is tightly coregulated with that of sGC alpha 1 in rat brain, while yet unknown additional regulatory mechanisms affect the Vmax of sGC. PMID: 12231239
9. sGC alpha(1) and beta(1) subunit protein levels in the ovary during postnatal development, gonadotropin-induced follicle growth, ovulation, and luteinization as well as in cultured rat granulosa cells PMID: 14749300
10. Results demonstrate that hypoxia decreases soluble guanylate cyclase alpha1 and beta1 expression and suggest that, in hypoxic vascular smooth muscle, decreased cyclic GMP synthesis may limit the vasodilator response to nitric oxide. PMID: 14754757
11. Soluble guanylate cyclases could be the target molecules for controlling neo-vascularization in a subset of human malignant gliomas. PMID: 15201957
12. Soluble guanylyl cyclase appears in a specific subset of periglomerular cells in the olfactory bulb. PMID: 15813955
13. Results identify and characterize the minimum functional ligand-binding heme domain derived from soluble guanylate cyclase. PMID: 16331987
14. for the function of sGC in vivo, where there is evidence for two nitric oxide-regulated activity states PMID: 17098738
15. Suggest that in coronary arterioles of obese rats, increased activity of sGC leads to an enhanced sensitivity to NO, which may contribute to the maintenance of NO-mediated dilations and coronary perfusion in obesity. PMID: 18408126
16. characterization of the promoter activity of human sGC alpha(1) and beta(1) subunits and identification of key transcription factors that govern subunit expression under basal and pro-inflammatory conditions and in the presence of ligand NO PMID: 18474600
17. Estradiol physiologically regulates sGC expression and activity in rat anterior pituitary gland. PMID: 19141686
18. beta1 is a multifunctional protein that regulates chromatin condensation and cell cycle progression, in addition to being an obligate monomer in functional nitric oxide-sensitive guanylyl cyclase heterodimers. PMID: 19433313
19. Soluble guanylyl cyclase activity is an important element not only in neurite outgrowth but also in synapse formation and maturation in cerebellar granule cells. PMID: 19461654
20. Report distinct molecular requirements for activation or stabilization of soluble guanylyl cyclase upon haem oxidation-induced degradation. PMID: 19466990

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KEGG: rno:25202

STRING: 10116.ENSRNOP00000062785

UniGene: Rn.87228