Rat Interleukin 1β,IL-1β ELISA Kit

This ELISA kit provides quantitative measurement of interleukin-1β (IL-1β) in rat samples, supporting research into innate immune signaling, neuroinflammation, and inflammatory disease models. Because IL-1β is a rapidly induced, tightly regulated cytokine whose circulating levels can vary dramatically between baseline and acute inflammatory states, selecting an assay with appropriate range and sensitivity is critical for accurate quantification across experimental conditions.

Detection Range: The 31.25–2000 pg/mL range spans from near-basal rat serum IL-1β concentrations through the elevated levels observed in LPS challenge, adjuvant-induced arthritis, and traumatic brain injury models, minimizing the need for serial dilutions or sample concentration in most in vivo paradigms.

Sensitivity: At 15.6 pg/mL, the kit detects IL-1β in unstimulated or sham-control rat samples where circulating levels are often low or sub-100 pg/mL, enabling meaningful fold-change calculations between treatment and control groups.

Sample Compatibility: Validation across serum, plasma, and tissue homogenates allows researchers to correlate systemic IL-1β levels with local tissue expression—for example, pairing plasma cytokine profiling with hippocampal or joint homogenate analysis within the same study.

Assay Efficiency: The 1–5 hour protocol and 50–100 µL sample volume accommodate small-volume rat plasma draws and limited tissue lysates typical of longitudinal or neonatal studies.

This kit is well suited for studies in experimental autoimmune models, sepsis, and neuroinflammatory injury research.