IL1B

IL1B, Interleukin-1 beta, is a key pro-inflammatory cytokine produced by various cells and has multiple biological functions such as regulating inflammatory responses, immune regulation, and tissue repair. IL1B initially exists in the form of inactive zymogen and needs to be converted into an active form through proteolytic processes, which are usually completed by the effector components of the inflammasome, caspases. The signaling pathways involved in IL1B mainly include the NF-κB signaling pathway and the MAPK signaling pathway. It initiates downstream signaling by binding to its receptor IL-1RI, leading to the expression of inflammatory factors and acute phase proteins. In addition, the mature form of IL1B is activated through the inflammasome pathway, in which the processing of pro-IL1β requires the activation of caspase-1. IL1B is produced and released after rapidly responding to inflammatory signals, and is closely related to the activation, proliferation, and differentiation of various immune and non-immune cells. It is an indispensable component in inflammatory and immune responses

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

The following IL1B reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

IL1B Antibodies

IL1B Proteins

IL1B ELISA Kits

IL1B Antibodies

IL1B Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA06574A0Rb	IL1B Antibody	Human	ELISA
CSB-PA06574B0Rb	IL1B Antibody, HRP conjugated	Human	ELISA
CSB-PA06574C0Rb	IL1B Antibody, FITC conjugated	Human
CSB-PA06574D0Rb	IL1B Antibody, Biotin conjugated	Human	ELISA
CSB-PA011614GA01HU	IL1B Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA003023	IL1B Antibody	Human,Mouse,Rat	WB, IHC, ELISA
CSB-PA005122	IL1B Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA829263	IL1B Antibody	Human,Mouse	ELISA,WB
CSB-PA825267	IL1B Antibody	Human,Mouse	ELISA,WB,IHC

IL1B Antibodies for Ovis aries (Sheep)

Code	Product Name	Species Reactivity	Application
CSB-PA011614HD01SH	IL1B Antibody, Biotin conjugated	Sheep	ELISA
CSB-PA011614HA01SH	IL1B Antibody	Sheep	ELISA, WB
CSB-PA011614YA01SH	IL1B Antibody	Sheep	ELISA, WB

IL1B Antibodies for Mus musculus (Mouse)

Code	Product Name	Species Reactivity	Application
CSB-PA17347C0Rb	Il1b Antibody, FITC conjugated	Mouse
CSB-PA17347A0Rb	Il1b Antibody	Mouse	ELISA

IL1B Proteins

IL1B Proteins for Capra hircus (Goat)

Code	Product Name	Source
CSB-YP011614GO CSB-EP011614GO CSB-BP011614GO CSB-MP011614GO CSB-EP011614GO-B	Recombinant Goat Interleukin-1 beta (IL1B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1B Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP011614MO CSB-EP011614MO CSB-BP011614MO CSB-MP011614MO CSB-EP011614MO-B	Recombinant Mouse Interleukin-1 beta (Il1b)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP003261MO	Recombinant Mouse Interleukin-1 beta protein (Il1b)	E.Coli
CSB-RP173474m	Recombinant Mouse Interleukin-1 beta (Il1b), partial	E.coli
CSB-AP004731MO	Recombinant Mouse Interleukin-1 beta (Il1b) (Active)	E.coli

IL1B Proteins for Oryctolagus cuniculus (Rabbit)

Code	Product Name	Source
CSB-YP011614RB CSB-EP011614RB CSB-BP011614RB CSB-MP011614RB CSB-EP011614RB-B	Recombinant Rabbit Interleukin-1 beta (IL1B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1B Proteins for Ovis aries (Sheep)

Code	Product Name	Source
CSB-EP011614SH	Recombinant Sheep Interleukin-1 beta (IL1B)	E.coli
CSB-YP011614SH	Recombinant Sheep Interleukin-1 beta (IL1B)	Yeast
CSB-BP011614SH CSB-MP011614SH CSB-EP011614SH-B	Recombinant Sheep Interleukin-1 beta (IL1B)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1B Proteins for Sus scrofa (Pig)

Code	Product Name	Source
CSB-YP011614PI CSB-EP011614PI CSB-BP011614PI CSB-MP011614PI CSB-EP011614PI-B	Recombinant Pig Interleukin-1 beta (IL1B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1B Proteins for Felis catus (Cat) (Felis silvestris catus)

Code	Product Name	Source
CSB-YP011614CA CSB-EP011614CA CSB-BP011614CA CSB-MP011614CA CSB-EP011614CA-B	Recombinant Cat Interleukin-1 beta (IL1B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1B Proteins for Macaca mulatta (Rhesus macaque)

Code	Product Name	Source
CSB-YP011614MOW CSB-EP011614MOW CSB-BP011614MOW CSB-MP011614MOW CSB-EP011614MOW-B	Recombinant Macaca mulatta (Rhesus macaque) Interleukin-1 beta (IL1B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP003081MOW	Recombinant Rhesus Macaque Interleukin-1 beta protein (IL1B) (Active)	E.coli

IL1B Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP011614BO CSB-EP011614BO CSB-BP011614BO CSB-MP011614BO CSB-EP011614BO-B	Recombinant Bovine Interleukin-1 beta (IL1B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1B Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP011614HU CSB-BP011614HU CSB-MP011614HU CSB-EP011614HU-B	Recombinant Human Interleukin-1 beta (IL1B)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP001671HU	Recombinant Human Interleukin-1 beta protein (IL1B) (Active)	E.coli
CSB-EP011614HU	Recombinant Human Interleukin-1 beta (IL1B)	E.coli
CSB-RP065744h	Recombinant Human Interleukin-1 beta (IL1B)	E.coli
CSB-EP011614HUe0	Recombinant Human Interleukin-1 beta (IL1B)	E.coli
CSB-EP011614HUa0	Recombinant Human Interleukin-1 beta protein (IL1B),Partial	E.coli

IL1B Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

Code	Product Name	Source
CSB-YP011614MOV CSB-EP011614MOV CSB-BP011614MOV CSB-MP011614MOV CSB-EP011614MOV-B	Recombinant Macaca fascicularis Interleukin-1 beta (IL1B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1B Proteins for Macaca nemestrina (Pig-tailed macaque)

Code	Product Name	Source
CSB-YP011614MOX CSB-EP011614MOX CSB-BP011614MOX CSB-MP011614MOX CSB-EP011614MOX-B	Recombinant Macaca nemestrina Interleukin-1 beta (IL1B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1B Proteins for Cervus elaphus (Red deer)

Code	Product Name	Source
CSB-YP011614DRN CSB-EP011614DRN CSB-BP011614DRN CSB-MP011614DRN CSB-EP011614DRN-B	Recombinant Cervus elaphus Interleukin-1 beta (IL1B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1B Proteins for Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)

Code	Product Name	Source
CSB-YP011614DRI CSB-EP011614DRI CSB-BP011614DRI CSB-MP011614DRI CSB-EP011614DRI-B	Recombinant Cercocebus atys Interleukin-1 beta (IL1B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1B Proteins for Mustela putorius furo (European domestic ferret) (Mustela furo)

Code	Product Name	Source
CSB-YP011614MOH CSB-EP011614MOH CSB-BP011614MOH CSB-MP011614MOH CSB-EP011614MOH-B	Recombinant Mustela putorius furo Interleukin-1 beta (IL1B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1B Proteins for Canis lupus familiaris (Dog) (Canis familiaris)

Code	Product Name	Source
CSB-YP630675DO CSB-EP630675DO CSB-BP630675DO CSB-MP630675DO CSB-EP630675DO-B	Recombinant Dog Interleukin-1 beta (IL1B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1B Proteins for Equus caballus (Horse)

Code	Product Name	Source
CSB-YP634668HO CSB-EP634668HO CSB-BP634668HO CSB-MP634668HO CSB-EP634668HO-B	Recombinant Horse Interleukin-1 beta (IL1B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP003481HO	Recombinant Horse Interleukin-1 beta protein (IL1B) (Active)	E.coli

IL1B Proteins for Pusa hispida (Ringed seal) (Phoca hispida)

Code	Product Name	Source
CSB-YP641327PAAZ CSB-EP641327PAAZ CSB-BP641327PAAZ CSB-MP641327PAAZ CSB-EP641327PAAZ-B	Recombinant Phoca hispida Interleukin-1 beta (IL1B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1B Proteins for Bubalus carabanensis (Swamp type water buffalo) (Bubalus bubalis carabanensis)

Code	Product Name	Source
CSB-YP643577BAAW CSB-EP643577BAAW CSB-BP643577BAAW CSB-MP643577BAAW CSB-EP643577BAAW-B	Recombinant Bubalus carabanensis Interleukin-1 beta (IL1B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1B Proteins for Rattus norvegicus (Rat)

Code	Product Name	Source
CSB-YP733920RA CSB-EP733920RA CSB-BP733920RA CSB-MP733920RA CSB-EP733920RA-B	Recombinant Rat Interleukin-1 beta (Il1b)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1B Proteins for Eumetopias jubatus (Steller sea lion) (Phoca jubata)

Code	Product Name	Source
CSB-YP740826EBAH CSB-EP740826EBAH CSB-BP740826EBAH CSB-MP740826EBAH CSB-EP740826EBAH-B	Recombinant Eumetopias jubatus Interleukin-1 beta (IL1B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1B Proteins for Phoca vitulina richardii (Pacific harbor seal)

Code	Product Name	Source
CSB-YP747506PHAB CSB-EP747506PHAB CSB-BP747506PHAB CSB-MP747506PHAB CSB-EP747506PHAB-B	Recombinant Phoca vitulina richardsi Interleukin-1 beta (IL1B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1B Proteins for Lama glama (Llama)

Code	Product Name	Source
CSB-YP801151LBS CSB-EP801151LBS CSB-BP801151LBS CSB-MP801151LBS CSB-EP801151LBS-B	Recombinant Lama glama Interleukin-1 beta (IL1B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1B Proteins for Delphinapterus leucas (Beluga whale)

Code	Product Name	Source
CSB-YP851948DJB CSB-EP851948DJB CSB-BP851948DJB CSB-MP851948DJB CSB-EP851948DJB-B	Recombinant Delphinapterus leucas Interleukin-1 beta (IL1B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1B Proteins for Trichosurus vulpecula (Brush-tailed possum)

Code	Product Name	Source
CSB-YP894065TQG CSB-EP894065TQG CSB-BP894065TQG CSB-MP894065TQG CSB-EP894065TQG-B	Recombinant Trichosurus vulpecula Interleukin-1 beta (IL1B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1B Proteins for Cavia porcellus (Guinea pig)

Code	Product Name	Source
CSB-YP894840GU CSB-EP894840GU CSB-BP894840GU CSB-MP894840GU CSB-EP894840GU-B	Recombinant Guinea pig Interleukin-1 beta (IL1B)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

IL1B ELISA Kit

IL1B ELISA Kit for Bos taurus (Bovine)

Code	Product Name	Sample Types	Sensitivity
CSB-E12986B	Bovine Interleukin 1β (IL- 1β) ELISA kit	serum, plasma, tissue homogenates	15.6 pg/mL

IL1B ELISA Kit for Canis lupus familiaris (Dog) (Canis familiaris)

Code	Product Name	Sample Types	Sensitivity
CSB-E13836c	Dog Interleukin 1β (IL- 1β) ELISA Kit	serum, plasma, cell culture supernates, tissue homogenates	1.95 pg/mL

IL1B ELISA Kit for Cavia porcellus (Guinea pig)

Code	Product Name	Sample Types	Sensitivity
CSB-EL011614GU	Guinea pig Interleukin-1 beta(IL1B) ELISA kit	serum, plasma, tissue homogenates	3.9 pg/mL

IL1B ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-E08053h	Human Interleukin 1β,IL-1β ELISA Kit	serum, plasma, tissue homogenates	1.95 pg/ml
CSB-E08053h-IS	Human Interleukin 1β,IL-1β ELISA Kit	serum, plasma, tissue homogenates, cell culture supernates	0.586 pg/ml

IL1B ELISA Kit for Mus musculus (Mouse)

Code	Product Name	Sample Types	Sensitivity
CSB-E08054m	Mouse Interleukin 1β,IL-1β ELISA Kit

IL1B ELISA Kit for Sus scrofa (Pig)

Code	Product Name	Sample Types	Sensitivity
CSB-E06782p	Pig Interleukin 1β,IL-1β ELISA Kit	serum, plasma, cell culture supernates, tissue homogenates	0.975 pg/mL

IL1B ELISA Kit for Oryctolagus cuniculus (Rabbit)

Code	Product Name	Sample Types	Sensitivity
CSB-E06900Rb	Rabbit Interleukin 1β,IL-1β ELISA Kit	serum, plasma, tissue homogenates	1.95 pg/mL

IL1B ELISA Kit for Rattus norvegicus (Rat)

Code	Product Name	Sample Types	Sensitivity
CSB-E08055r	Rat Interleukin 1β,IL-1β ELISA Kit	serum, plasma, tissue homogenates.	0.039 ng/ml.

IL1B ELISA Kit for Ovis aries (Sheep)

Code	Product Name	Sample Types	Sensitivity
CSB-E10115Sh	Sheep Interleukin 1β,IL-1β ELISA Kit	serum, plasma, tissue homogenates	3.9 pg/mL

IL1B ELISA Kit for Capra hircus (Goat)

Code	Product Name	Sample Types	Sensitivity
CSB-E16568G	Goat Interleukin 1β(IL-1β) ELISA Kit	serum, plasma, tissue homogenates	0.78 pg/mL

IL1B ELISA Kit for Fish

Code	Product Name	Sample Types	Sensitivity
CSB-E13259Fh	Fish Interleukin 1β (IL- 1β) ELISA Kit	serum, plasma, tissue homogenates	0.78 pg/mL

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