Recombinant Human Bone morphogenetic protein 2(BMP2) (Active)

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Code CSB-AP003991HU
Product Type Growth Factor
Size $195Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P12643
Image
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Storage Buffer Lyophilized from a 0.2 μm Filtered 10 mM NH4-HAC, pH 4.0
Alias Bone Morphogenetic Protein 2; BMP-2; Bone Morphogenetic Protein 2A; BMP-2A; BMP2; BMP2A
Species Homo sapiens (Human)
Biological_Activity The ED50 as determined by the cytolysis of MC3T3-E1 cells is less than 2 μg/ml
Purity Greater than 95% as determined by SDS-PAGE.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence QAKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
Research Area Signal Transduction
Source E.coli
Gene Names BMP2
Expression Region 283-396aa
Tag Info Tag-Free
Mol. Weight 13.3 kDa
Protein Description Full Length of Mature Protein
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Function Induces cartilage and bone formation
Subcellular Location Secreted
Protein Families TGF-beta family
Tissue Specificity Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.
Database Links

HGNC: 1069

OMIM: 112261

KEGG: hsa:650

STRING: 9606.ENSP00000368104

UniGene: Hs.73853

Pathway Hippo signaling pathway
TGF-beta signaling pathway

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