Recombinant Human Inhibin beta A chain(INHBA) (Active)

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Code CSB-AP004011HU
Product Type Growth Factor
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Uniprot No. P08476
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  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Storage Buffer Lyophilized from a 0.2 μm filtered 1xPBS, pH 7.4
Alias Inhibin beta A chain;INHBA;Activin A
Species Homo sapiens (Human)
Biological_Activity The ED50 as determined by its ability to binding Activin IIB used funtional ELISA is 26.3 ug/ml when Activin A 1ug/ml in a solid phases.
Purity Greater than 95% as determined by SDS-PAGE.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence GLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
Research Area Immunology
Source Mammalian cell
Gene Names INHBA
Expression Region 311-426aa
Tag Info Tag-Free
Mol. Weight 13 kDa
Protein Description Full Length of Mature Protein
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Function Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
Subcellular Location Secreted
Protein Families TGF-beta family
Database Links

HGNC: 6066

OMIM: 147290

KEGG: hsa:3624

STRING: 9606.ENSP00000242208

UniGene: Hs.28792

Pathway TGF-beta signaling pathway
Signaling pathways regulating pluripotency of stem cells

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