Recombinant Human Parathyroid hormone protein(PTH),15N Stable Isotope Labeled(Active)

Code CSB-AP000041HU
Product Type Hormone
Size Pls inquiry other sizesPurchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P01270
Image
Storage Buffer 0.2 μm filtered PBS, pH 7.4 ,lyophilized
Alias PTH, Parathyrin
Species Homo sapiens (Human)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by its ability to induce cAMP accumulation in murine MC3T3E1 cells is less than 50 ng/ml, corresponding to a specific activity of >2.0x104 IU/mg.
Purity >97% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence SVSEIQLMHN LGKHLNSMER VEWLRKKLQD VHNFVALGAP LAPRDAGSQR PRKKEDNVLV ESHEKSLGEA DKADVNVLTK AKSQ
Research Area Signal Transduction
Source E.Coli
Gene Names PTH
Expression Region 32-115aa
Product Info Tag-Free
Mol. Weight 9.5 kDa
Protein Description Full Length of Mature Protein
PubMed ID 6950381; 6220408; 15489334; 7829495; 4833516; 15340161; 4521809; 728431; 1125201; 4474131; 4721748; 21076856; 2069952; 8344299; 7797503; 10623601; 10837469; 18375760; 2212001; 10523031; 18056632
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Function PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.
Involvement in disease Hypoparathyroidism, familial isolated (FIH)
Subcellular location Secreted

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