Recombinant Human interleukin-16 proein(IL16) (Active)

In Stock
Code CSB-AP001641HU
Product Type Interleukin
Size US$112Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. Q14005
Lead Time 5-10 business days
Image
Storage Buffer 0.2 μm filtered PBS, pH 7.4, lyophilized
Alias IL-16, LCF,]
Species Homo sapiens (Human)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 1.0 pg/ml, corresponding to a specific activity of >1.0x109 IU/mg.
Purity >95% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence SAASASAASD VSVESTAEAT VCTVTLEKMS AGLGFSLEGG KGSLHGDKPL TINRIFKGAA SEQSETVQPG DEILQLGGTA MQGLTRFEAW NIIKALPDGP VTIVIRRKSL QSKETTAAGD S
Research Area Immunology
Source E.coli
Gene Names IL16
Expression Region 1212-1332aa
Tag Info Tag-Free
Mol. Weight 12.4 kDa
Protein Description Full Length of Mature Protein
PubMed ID 12923170; 19906316; 14702039; 16572171; 15489334; 9990060; 8609984; 7910967; 9422780; 11032842; 11276202; 12450396; 12620798; 14734747; 18097041; 21269460; 24275569; 9699630;
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Function Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.; FUNCTION
Subcellular Location Interleukin-16: Secreted, SUBCELLULAR LOCATION: Isoform 1: Cytoplasm, SUBCELLULAR LOCATION: Isoform 3: Cytoplasm, Nucleus
Tissue Specificity Isoform 3 is expressed in hemopoietic tissues, such as resting T-cells, but is undetectable during active T-cell proliferation.
Database Links

HGNC: 5980

OMIM: 603035

KEGG: hsa:3603

STRING: 9606.ENSP00000302935

UniGene: Hs.459095

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