COL4A1 Monoclonal Antibody

Datasheet
Code CSB-MA457742
Product Type Monoclonal Antibody
Size US$167
Uniprot No. p02462
Research Use Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Image
  • Immunohistochemical analysis of paraffin-embedded Human Kidney Tissue using Collagen IV Mouse mAb diluted at 1:200.

  • Immunohistochemical analysis of paraffin-embedded Human Skin Tissue using Collagen IV Mouse mAb diluted at 1:200.

Immunogen Synthetic Peptide
Raised in Mouse
Species Reactivity Human,Mouse,Rat
Tested Applications ELISA,IHC;Recommended dilution:IHC:1:50-1:200
Form Liquid
Conjugate Non-conjugated
Storage Buffer PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Purification Method The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Alias Collagen alpha-1(IV) chain [Cleaved into: Arresten]
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
Involvement in disease Brain small vessel disease with or without ocular anomalies (BSVD); Hereditary angiopathy with nephropathy aneurysms and muscle cramps (HANAC); Porencephaly 1 (POREN1); Intracerebral hemorrhage (ICH); Tortuosity of retinal arteries (RATOR); Schizencephaly (SCHZC)
Subcellular Location Secreted, extracellular space, extracellular matrix, basement membrane
Protein Families Type IV collagen family
Tissue Specificity Highly expressed in placenta.
Database Links

HGNC: 2202

OMIM: 120130

KEGG: hsa:1282

STRING: 9606.ENSP00000364979

UniGene: Hs.17441

Pathway PI3K-Akt signaling pathway
Focal adhesion
AGE-RAGE signaling pathway in diabetic complications

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