S100B Monoclonal Antibody

Datasheet
Code CSB-MA106771A0m
Product Type Monoclonal Antibody
Size US$350Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P04271
Immunogen Recombinant Human S100B protein
Raised in mouse
Species Reactivity Human
Specificity specific for S100B denatured forms
Tested Applications ELISA
Relevance Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
Form liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method >95%,protein G purifed
Isotype IgG1
Clonality monoclonal
Alias S100B ,S-100 protein beta chain,S-100 protein subunit beta,S100 calcium-binding protein B
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Gene Names S100B
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Clone No. 1A1B1
Still Have Questions? Leave a Message or Start an on-line Chat
Function Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
Subcellular Location Cytoplasm, Nucleus
Protein Families S-100 family
Tissue Specificity Although predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues.
Database Links

HGNC: 10500

OMIM: 176990

KEGG: hsa:6285

STRING: 9606.ENSP00000291700

UniGene: Hs.422181

Related Products

S100B Antibodies

S100B Antibodies for Human

S100B Antibodies for Homo sapiens (Human)

S100B Proteins

S100B Proteins for Homo sapiens (Human)

S100B ELISA Kit

S100B ELISA Kit for Homo sapiens (Human)

Most popular with customers

Newsletters

Get all the latest information on Events, Sales and Offers. Sign up for newsletter today.

Copyright © 2007-2018 www.cusabio.com CUSABIO TECHNOLOGY LLC All Rights Reserved.

Wait!

Join the 25,000 subscribers to get research hotpots, technical tips, latest information on events, sales and offers.

Sign up now!

We don't deal in spam.