Greater than 95% as determined by SDS-PAGE.
Less than 1.0 EU/ug as determined by LAL method.
Measured by its binding ability in a functional ELISA. Immobilized MERTK at 2 μg/mL can bind anti-MERTK antibody（CSB-RA621519A1HU）, the EC50 is 32.95-48.25 ng/mL.
(Proto-oncogene c-Mer) (Receptor tyrosine kinase MerTK)
Homo sapiens (Human)
Target Protein Sequence
Note: We will preferentially ship the format that
we have in stock, however, if you have any special requirement for the format, please remark your
requirement when placing the order, we will prepare according to your demand.
Lyophilized from a 0.2 μm filtered 20 mM Tris-HCl, 0.5 M NaCl, 0.2 M Arg, 6% Trehalose, pH 8.0
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature
and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized
form is 12 months at -20°C/-80°C.
Basically, we can dispatch the products out in 3-7 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA
Please contact us to get it.
The MERTK protein CSB-MP621519HU is a recombinant human protein produced in mammalian cells. It is a partial length protein containing amino acids Ala21-Ile505 of the human MERTK and is labeled with 10xHis-tag at the C-terminus. This MERTK protein is biologically active, low in endotoxin content (less than 1EU/µg), and high in purity (greater than 95%). In the functional ELISA, this MERTK can bind to the anti-MERTK antibody with the EC50 of 32.95-48.25 ng/mL. It showed an apparent molecular weight of about 90 kDa on the gel.
MERTK is a member of the receptor tyrosine kinase family which is widely expressed in many tissues throughout the body. MERTK is involved in various biological processes, including the modulation of apoptosis, proliferation, migration, and invasion of cells. These processes are regulated mainly through the PI3K-Akt signaling pathway and MAPK signaling pathway. Increasing evidence has found that the regulation of MERTK-mediated signaling pathways can promote tumor cell apoptosis and inhibit tumor cell proliferation, invasion, migration, and angiogenesis. Targeting drug cancer therapy based on the MERTK signaling pathway has gradually become a hotspot of clinical research.