MERTK (Mer Tyrosine Kinase) is a tyrosine kinase receptor belonging to the Tyro3-Axl-Mer (TAM) family. MERTK plays a crucial role in cell signaling and the immune system, particularly in the function and regulation of phagocytic cells such as macrophages. MERTK also has a role in the immune system, especially in regulating the activation and function of immune cells. It can influence the regulation of immune cells to maintain immune balance. Aberrant MERTK signaling is associated with certain diseases and disease states, such as autoimmune diseases, inflammatory conditions, and cancer. Therefore, MERTK is considered a potential therapeutic target. Some drugs and treatment approaches are under investigation to intervene in MERTK signaling for the treatment of related diseases.
● Recombinant Human Tyrosine-protein kinase Mer(MERTK),partial (Active) CSB-MP621519HU
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized MERTK at 2 μg/ml can bind anti-MERTK antibody(CSB-RA621519A1HU), the EC50 is 32.95-48.25 ng/mL.
● Recombinant Mouse Tyrosine-protein kinase Mer(Mertk),partial (Active) CSB-MP723346MO
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity: Measured by its binding ability in a functional ELISA. Immobilized Mouse Mertk at 2 μg/ml can bind anti-MERTK recombinant antibody(CSB-RA621519A1HU), the EC50 is 19.22-25.80 ng/mL.
● MERTK Recombinant Monoclonal Antibody CSB-RA621519A1HU
Validated Data
The Binding Activity of MERTK with anti-MERTK antibody.
Activity: Measured by its binding ability in a functional ELISA. Immobilized MERTK at 2 μg/mL can bind anti-MERTK antibody(CSB-RA621519A1HU), the EC50 is 41.31-72.08 ng/mL.
The following MERTK reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
MERTK Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA038071 | Phospho-MERTK/TYRO3 (Tyr749/681) Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA114581 | MERTK/TYRO3 (Ab-753) Antibody |
Human,Mouse,Rat | ELISA,WB |
CSB-PA253602 | MERTK Antibody |
Human | ELISA,WB |
CSB-PA621519ESR2HU | MERTK Antibody |
Human, Mouse | ELISA, WB, IHC |
CSB-PA621519ESR1HU | MERTK Antibody |
Human, Mouse | ELISA, WB |
CSB-PA003228 | MERTK Antibody |
Human | WB, ELISA |
CSB-PA999740 | MERTK Antibody |
Human,Mouse,Rat | ELISA,IHC |
CSB-PA668039 | MERTK Antibody |
Human,Mouse,Rat | ELISA,IHC |
CSB-RA621519A1HU | MERTK Recombinant Monoclonal Antibody |
Human | ELISA |
CSB-MA621519A0m | MERTK Monoclonal Antibody |
Human | ELISA, WB, IHC, IF, FC |
MERTK Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP621519HU | Recombinant Human Tyrosine-protein kinase Mer (MERTK), partial,Yeast |
Yeast |
CSB-EP621519HU CSB-BP621519HU CSB-MP621519HU CSB-EP621519HU-B |
Recombinant Human Tyrosine-protein kinase Mer (MERTK), partial |
E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-MP621519HU | Recombinant Human Tyrosine-protein kinase Mer (MERTK), partial (Active) |
Mammalian cell |