AADAC Antibody

Datasheet
Code CSB-PA001014LA01HU
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Uniprot No. P22760
Image
  • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA001014LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA001014LA01HU at dilution of 1:100

Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunogen Recombinant Human Arylacetamide deacetylase protein (24-399AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA, IHC; Recommended dilution: IHC:1:20-1:200
Relevance Displays cellular triglyceride lipase activity in liver, increases the levels of intracellular fatty acids derived from the hydrolysis of newly formed triglyceride stores and plays a role in very low-density lipoprotein assembly. Displays serine esterase activity in liver. Deacetylates a variety of arylacetamide substrates, including xenobiotic compounds and procarcinogens, converting them to the primary arylamide compounds and increasing their toxicity.
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Arylacetamide deacetylase (EC 3.1.1.3), AADAC, DAC
Immunogen Species Human
Research Area Signal Transduction
Target Names AADAC
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Displays cellular triglyceride lipase activity in liver, increases the levels of intracellular fatty acids derived from the hydrolysis of newly formed triglyceride stores and plays a role in very low-density lipoprotein assembly. Displays serine esterase activity in liver. Deacetylates a variety of arylacetamide substrates, including xenobiotic compounds and procarcinogens, converting them to the primary arylamide compounds and increasing their toxicity.
Subcellular Location Endoplasmic reticulum membrane, Single-pass type II membrane protein, Microsome membrane, Single-pass type II membrane protein
Protein Families 'GDXG' lipolytic enzyme family
Tissue Specificity Detected in liver (at protein level). Mainly expressed in liver, small intestine, colon, adrenal gland and bladder.
Database Links

HGNC: 17

OMIM: 600338

KEGG: hsa:13

STRING: 9606.ENSP00000232892

UniGene: Hs.506908

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