Your Good Partner in Biology Research
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Your Good Partner in Biology Research
| Code | CSB-PA001076ESR2HU |
| Size |
US$167Purchase it in Cusabio online store (Shop online in the US. Customers outside the US, please order from local distributors.) |
| Uniprot No. | P61221 |
| Image |
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| Protocols | ELISA Protocol Western Blotting(WB) Protocol Immunohistochemistry (IHC) Protocol |
| Immunogen | Recombinant Human ATP-binding cassette sub-family E member 1 protein (320-599AA) |
| Raised in | Rabbit |
| Species Reactivity | Human |
| Tested Applications | ELISA, WB, IHC; Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200 |
| Relevance | Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly. |
| Form | Liquid |
| Conjugate | Non-conjugated |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Purification Method | Antigen Affinity Purified |
| Isotype | IgG |
| Clonality | Polyclonal |
| Alias | ATP-binding cassette sub-family E member 1 (2'-5'-oligoadenylate-binding protein) (HuHP68) (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I), ABCE1, RLI RNASEL1 RNASELI RNS4I |
| Immunogen Species | Human |
| Research Area | Signal Transduction |
| Target Names | ABCE1 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
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| Function | Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly. |
| Subcellular Location | Cytoplasm, Mitochondrion |
| Protein Families | ABC transporter superfamily, ABCE family |
| Database Links |
HGNC: 69 OMIM: 601213 KEGG: hsa:6059 STRING: 9606.ENSP00000296577 UniGene: Hs.12013 |
ABCE1 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA001076GA01HU | ABCE1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA591967 | ABCE1 Antibody | Human,Mouse | ELISA,WB |
| CSB-PA802152 | ABCE1 Antibody | Human,Mouse | ELISA,WB |
ABCE1 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP001076HU CSB-EP001076HU CSB-BP001076HU CSB-MP001076HU |
Recombinant Human ATP-binding cassette sub-family E member 1(ABCE1) | Yeast E.coli Baculovirus Mammalian cell |
2-hydroxyisobutyryl-HIST1H2BC (K12) Antibody
Applications: ELISA, WB, ICC, IF
Species Reactivity: Human
2-hydroxyisobutyryl-HIST1H3A (K27) Antibody
Applications: ELISA, WB, ICC, IF
Species Reactivity: Human
2-hydroxyisobutyryl-HIST1H4A (K16) Antibody
Applications: ELISA, WB, IF, IP, ChIP
Species Reactivity: Human
