ACADL Antibody

Code CSB-PA001125GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
ACADL
Alternative Names
ACAD4 antibody; ACADL antibody; ACADL_HUMAN antibody; Acyl Coenzyme A dehydrogenase long chain antibody; Acyl-CoA dehydrogenase long chain antibody; FLJ94052 antibody; LCAD antibody; Long chain acyl CoA dehydrogenase antibody; Long-chain specific acyl-CoA dehydrogenase; mitochondrial antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Human ACADL
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Ammonium Sulfate Precipitation
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Long-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, long-chain specific acyl-CoA dehydrogenase can act on saturated and unsaturated acyl-CoAs with 6 to 24 carbons with a preference for 8 to 18 carbons long primary chains.
Gene References into Functions
  1. the fatty acid oxidation pathway and LCAD are factors contributing to the pathophysiology of pulmonary disease PMID: 24591516
  2. Sirtuin 3 (SIRT3) protein regulates long-chain acyl-CoA dehydrogenase by deacetylating conserved lysines near the active site. PMID: 24121500
  3. LCAD is minimally expressed in human skeletal muscle and likely does not play a significant role in long-chain fatty acid oxidation. PMID: 20363655
Involvement in disease
Acyl-CoA dehydrogenase very long-chain deficiency (ACADVLD)
Subcellular Location
Mitochondrion matrix.
Protein Families
Acyl-CoA dehydrogenase family
Database Links

HGNC: 88

OMIM: 609576

KEGG: hsa:33

STRING: 9606.ENSP00000233710

UniGene: Hs.471277

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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