Acyl-CoA dehydrogenase, long chain is a protein that in humans is encoded by the ACADL gene. The LCAD enzyme catalyzes most of fatty acid beta-oxidation by forming a C2-C3 trans-double bond in the fatty acid. LCAD works on long-chain fatty acids, typically between C12 and C16-acylCoA. LCAD is essential for oxidizing unsaturated fatty acids such as oleic acid, but seems redundant in the oxidation of saturated fatty acids. Fatty acid oxidation has proven to spare glucose in fasting conditions, and is also required for amino acid metabolism, which is essential for the maintenance of adequate glucose production. LCAD is regulated by a reversible acetylation mechanism by SIRT3, in which the active form of the enzyme is deacetylated, and hyperacetylation reduces the enzymatic activity.
The following ACADL reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
ACADL Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA010120GA01HU | ACADL Antibody |
Human | ELISA,WB |
CSB-PA001125GA01HU | ACADL Antibody |
Human | ELISA,WB |
CSB-PA001125LA01HU | ACADL Antibody |
Human, Mouse | ELISA, WB, IHC |
ACADL Proteins for Sus scrofa (Pig)
Code | Product Name | Source |
---|---|---|
CSB-YP001125PI CSB-EP001125PI CSB-BP001125PI CSB-MP001125PI CSB-EP001125PI-B |
Recombinant Pig Long-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADL) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ACADL Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP001125RA CSB-EP001125RA CSB-BP001125RA CSB-MP001125RA CSB-EP001125RA-B |
Recombinant Rat Long-chain specific acyl-CoA dehydrogenase, mitochondrial (Acadl) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ACADL Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP001125HU CSB-EP001125HU CSB-BP001125HU CSB-MP001125HU CSB-EP001125HU-B |
Recombinant Human Long-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADL) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ACADL Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP001125MO CSB-EP001125MO CSB-BP001125MO CSB-MP001125MO CSB-EP001125MO-B |
Recombinant Mouse Long-chain specific acyl-CoA dehydrogenase, mitochondrial (Acadl) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ACADL Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Code | Product Name | Source |
---|---|---|
CSB-YP730706MOV CSB-EP730706MOV CSB-BP730706MOV CSB-MP730706MOV CSB-EP730706MOV-B |
Recombinant Macaca fascicularis Long-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADL) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |