ACADL Antibody

Code CSB-PA001125LA01HU
Size US$166
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  • Western blot
    All lanes: ACADL antibody at 8µg/ml
    Lane 1: Mouse kidney tissue
    Lane 2: Mouse heart tissue
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 48 kDa
    Observed band size: 48 kDa

  • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA001125LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA001125LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ACADL Polyclonal antibody
Uniprot No.
Target Names
ACADL
Alternative Names
ACAD4 antibody; ACADL antibody; ACADL_HUMAN antibody; Acyl Coenzyme A dehydrogenase long chain antibody; Acyl-CoA dehydrogenase long chain antibody; FLJ94052 antibody; LCAD antibody; Long chain acyl CoA dehydrogenase antibody; Long-chain specific acyl-CoA dehydrogenase; mitochondrial antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Long-chain specific acyl-CoA dehydrogenase, mitochondrial protein (30-260AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The ACADL Antibody (Product code: CSB-PA001125LA01HU) is Non-conjugated. For ACADL Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA001125LB01HU ACADL Antibody, HRP conjugated ELISA
FITC CSB-PA001125LC01HU ACADL Antibody, FITC conjugated
Biotin CSB-PA001125LD01HU ACADL Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Long-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, long-chain specific acyl-CoA dehydrogenase can act on saturated and unsaturated acyl-CoAs with 6 to 24 carbons with a preference for 8 to 18 carbons long primary chains.
Gene References into Functions
  1. the fatty acid oxidation pathway and LCAD are factors contributing to the pathophysiology of pulmonary disease PMID: 24591516
  2. Sirtuin 3 (SIRT3) protein regulates long-chain acyl-CoA dehydrogenase by deacetylating conserved lysines near the active site. PMID: 24121500
  3. LCAD is minimally expressed in human skeletal muscle and likely does not play a significant role in long-chain fatty acid oxidation. PMID: 20363655
Involvement in disease
Acyl-CoA dehydrogenase very long-chain deficiency (ACADVLD)
Subcellular Location
Mitochondrion matrix.
Protein Families
Acyl-CoA dehydrogenase family
Database Links

HGNC: 88

OMIM: 609576

KEGG: hsa:33

STRING: 9606.ENSP00000233710

UniGene: Hs.471277

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