AIFM2 Antibody, HRP conjugated

Datasheet
Code CSB-PA874794LB01HU
Size US$299
Uniprot No. Q9BRQ8
Protocols ELISA Protocol
Immunogen Recombinant Human Apoptosis-inducing factor 2 protein (110-373AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Oxidoreductase, which may play a role in mediating a p53/TP53-dependent apoptosis response. Probable oxidoreductase that acts as a caspase-independent mitochondrial effector of apoptotic cell death. Binds to DNA in a sequence-independent manner. May contribute to genotoxin-induced growth arrest.
Form Liquid
Conjugate HRP
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Antigen Affinity Purified
Isotype IgG
Clonality Polyclonal
Alias Apoptosis-inducing factor 2 (EC 1.-.-.-) (Apoptosis-inducing factor homologous mitochondrion-associated inducer of death) (Apoptosis-inducing factor-like mitochondrion-associated inducer of death) (p53-responsive gene 3 protein), AIFM2, AMID PRG3
Immunogen Species Homo sapiens (Human)
Research Area Cell Biology
Target Names AIFM2
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Oxidoreductase, which may play a role in mediating a p53/TP53-dependent apoptosis response. Probable oxidoreductase that acts as a caspase-independent mitochondrial effector of apoptotic cell death. Binds to DNA in a sequence-independent manner. May contribute to genotoxin-induced growth arrest.
Subcellular Location Cytoplasm, Mitochondrion outer membrane, Membrane, Lipid-anchor
Protein Families FAD-dependent oxidoreductase family
Tissue Specificity Detected in most normal tissues as two transcripts of 1.8 and 4.0 kb in length, respectively. Highly expressed in heart, moderately in liver and skeletal muscles, and expressed at low levels in placenta, lung, kidney, and pancreas. Both transcripts expres
Database Links

HGNC: 21411

OMIM: 605159

KEGG: hsa:84883

STRING: 9606.ENSP00000312370

UniGene: Hs.650680

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