ALDH3B1 Antibody

Datasheet

Code	CSB-PA001574LA01HU
Size	US$166
	Order now
Image	Western Blot Positive WB detected in: K562 whole cell lysate, Rat kidney tissue, Rat spleen tissue, Mouse stomach tissue All lanes: ALDH3B1 antibody at 3µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 52, 48 kDa Observed band size: 52 kDa Immunofluorescent analysis of A549 cells using CSB-PA001574LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
The Latest Promotion
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ALDH3B1 Polyclonal antibody

Uniprot No.

P43353

Target Names

ALDH3B1

Alternative Names

ALDH3B1 antibody; ALDH7Aldehyde dehydrogenase family 3 member B1 antibody; EC 1.2.1.28 antibody; EC 1.2.1.5 antibody; EC 1.2.1.7 antibody; Aldehyde dehydrogenase 7 antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Human Aldehyde dehydrogenase family 3 member B1 protein (168-449AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The ALDH3B1 Antibody (Product code: CSB-PA001574LA01HU) is Non-conjugated. For ALDH3B1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA001574LB01HU	ALDH3B1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA001574LC01HU	ALDH3B1 Antibody, FITC conjugated
Biotin	CSB-PA001574LD01HU	ALDH3B1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IF

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000
IF	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Description

CUSABIO is glad to provide a highly specific antibody directed against an epitope of human ALDH3B1 protein. The polyclonal antibody (CSB-PA001574LA01HU) is raised in the rabbit against a peptide mapping within amino acid residues 168-449 of human ALDH3B1. It exists as an unconjugated IgG isotype. Its purity is 95%+ using protein G purified. This ALDH3B1 antibody has undergone rigorous quality validations in ELISA, IF, and WB analyses. And it has been designed to recognize ALDH3B1 from human, mouse, and rat samples. Its target protein plays an important role in the defense against oxidative stress, specifically lipid peroxidation-derived aldehydes.

Customer Reviews and Q&A

■ Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function

Oxidizes medium and long chain saturated and unsaturated aldehydes. Metabolizes also benzaldehyde. Low activity towards acetaldehyde and 3,4-dihydroxyphenylacetaldehyde. May not metabolize short chain aldehydes. Can use both NADP(+) and NAD(+) as electron acceptor. May have a protective role against the cytotoxicity induced by lipid peroxidation.

Gene References into Functions

the likely physiological function of ALDH3B1 is to oxidize lipid-derived aldehydes generated in the plasma membrane and not to be involved in the sphingolipid metabolism in the endoplasmic reticulum. PMID: 23721920
protects cells from the damaging effects of oxidative stress PMID: 20699116
The specificity of ALDH3B1 distribution may prove to be directly related to the functional role of this enzyme in human tissues. PMID: 20729348
This study shows for the first time the functionality, expression and protective role of ALDH3B1 and indicates a potential physiological role of ALDH3B1 against oxidative stress. PMID: 17382292
These findings provided convincing evidence that epistasis between the catechol-O-methyltransferase and aldehyde dehydrogenase 3B1 genes plays an important role in the pathogenesis of schizophrenia PMID: 19159868
Initial characterization of human ALDH3B1 suggests a potential physiological role of this protein in oxidative stress processes. PMID: 17382292

Hide All

Subcellular Location

Cell membrane; Lipid-anchor. Note=Primarily in the plasma membrane as well as in some punctate structures in the cytoplasm.

Protein Families

Aldehyde dehydrogenase family

Tissue Specificity

Highest expression in kidney and lung.

Database Links

HGNC: 410

OMIM: 600466

KEGG: hsa:221

UniGene: Hs.523841

Promotions

Transmembrane Protein Questionnaire with Gifts

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

Join us with

Subscribe newsletter

Leave a message

Message

Product >> Product Name：
Product >> Code：
Name： *
Email： *
Company/Organization：
Phone：
Since emails may get flagged by spam filters occasionally, we recommend leaving your phone number as a precaution. Your information is safe with us.
Question/Comment： *
Your Region： *
I'd like to receive email newsletters from Cusabio

Yes

No
How do you know CUSABIO?

Email

Distributor

Search engine

Advertisement

Others
CAPTCHA verification：

Place an order now

I. Product details

Product name *

Code *

Size *

Quantity *

Message

II. Contact details

Name *

Email address *

Company/Organization

Phone

III. Ship To

Address *

City *

State/Province *

Zip/Post code *

Country *

Attn Name *

Phone# *

IV. Bill To Same as Shipping Address