ALDH4A1 Antibody

Datasheet

Code	CSB-PA935612
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA935612(ALDH4A1 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA935612(ALDH4A1 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: ×200) Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human fetal liver tissue, Human liver cancer tissue, Primary antibody: CSB-PA935612(ALDH4A1 Antibody) at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
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Product Details
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Target Background

Product Details

Uniprot No.

P30038

Target Names

ALDH4A1

Alternative Names

AL4A1_HUMAN antibody; aldehyde dehydrogenase 4 antibody; aldehyde dehydrogenase 4 family; member A1 antibody; Aldehyde dehydrogenase family 4 member A1 antibody; Aldehyde dehydrogenase; family 4; subfamily A; member 1 antibody; ALDH4 antibody; aldh4a1 antibody; Delta 1 pyrroline 5 carboxylate dehydrogenase; mitochondrial antibody; Delta-1-pyrroline-5-carboxylate dehydrogenase antibody; L-glutamate gamma-semialdehyde dehydrogenase antibody; mitochondrial antibody; mitochondrial delta-1-pyrroline 5-carboxylate dehydrogenase antibody; P5C dehydrogenase antibody; P5CD antibody; P5CDh antibody; P5CDhL antibody; P5CDhS antibody; Pyrroline-5-carboxylate dehydrogenase antibody; RP11 128M10.1 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Fusion protein of Human ALDH4A1

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,WB,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:2000-1:5000
WB	1:500-1:2000
IHC	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes.

Gene References into Functions

the impact of the hyperprolinemia-associated mutation of Ser352 to Leu on the structure and catalytic properties of the P5CDH PMID: 22516612
ALDH4 is a p53-inducible gene with a protective role in cellular stresses PMID: 14986171
ALDH4 is transcriptionally induced by p53. PMID: 14986171

Involvement in disease

Hyperprolinemia 2 (HYRPRO2)

Subcellular Location

Mitochondrion matrix.

Protein Families

Aldehyde dehydrogenase family

Tissue Specificity

Highest expression is found in liver followed by skeletal muscle, kidney, heart, brain, placenta, lung and pancreas.

Database Links

HGNC: 406

OMIM: 239510

KEGG: hsa:8659

STRING: 9606.ENSP00000290597

UniGene: Hs.77448

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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