ANAPC10 Antibody

Code CSB-PA892350ESR2HU
Size US$299Purchase it in Cusabio online store
(only available for customers from the US)
  • Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA892350ESR2HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA892350ESR2HU at dilution of 1:100

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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) ANAPC10 Polyclonal antibody
Uniprot No. Q9UM13
Target Names ANAPC10
Alternative Names ANAPC 10 antibody; anapc10 antibody; Anaphase promoting complex 10 antibody; Anaphase promoting complex subunit 10 antibody; Anaphase-promoting complex subunit 10 antibody; Apc 10 antibody; APC10 antibody; APC10_HUMAN antibody; Cyclosome subunit 10 antibody; DKFZP564L0562 antibody; Doc 1 antibody; Doc1 antibody; Doc1; S. cerevisiae; homolog of antibody; OTTHUMP00000220297 antibody; OTTHUMP00000220298 antibody; OTTHUMP00000220299 antibody; OTTHUMP00000220300 antibody; OTTHUMP00000220303 antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Anaphase-promoting complex subunit 10 protein (1-185AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Antigen Affinity Purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form Liquid
Tested Applications ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Gene References into Functions
  1. Cdc20 requires APC3 and APC8 to bind and activate the APC/C when the spindle assembly checkpoint is satisfied, but only APC8 when active, and APC10 is crucial for the destruction of cyclin B1 and securin, but not cyclin A PMID: 21336306
  2. Substrates are recruited to the Anaphase-promoting complex by binding to a bipartite substrate receptor composed of Cdh1 and Doc1. PMID: 21186364
Protein Families APC10 family
Database Links

HGNC: 24077

OMIM: 613745

KEGG: hsa:10393

STRING: 9606.ENSP00000310071

UniGene: Hs.480876


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