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| Code | CSB-PA001696GA01HU |
| Size | US$685 How to order? |
| Have Questions? | Leave a Message or Start an on-line Chat |
| Uniprot No. | Q9NYG5 |
| Target Names | ANAPC11 |
| Alternative Names | ANAPC 11 antibody; ANAPC11 antibody; Anaphase promoting complex subunit 11 (yeast APC11 homolog) antibody; Anaphase promoting complex subunit 11 antibody; Anaphase promoting complex subunit 11 homolog (yeast) antibody; Anaphase promoting complex subunit 11 homolog antibody; Anaphase-promoting complex subunit 11 antibody; Apc 11 antibody; Apc 11p antibody; APC11 anaphase promoting complex subunit 11 homolog (yeast) antibody; APC11 anaphase promoting complex subunit 11 homolog antibody; APC11 antibody; APC11_HUMAN antibody; Apc11p antibody; Cyclosome subunit 11 antibody; Hepatocellular carcinoma associated RING finger protein antibody; Hepatocellular carcinoma-associated RING finger protein antibody; HSPC 214 antibody; HSPC214 antibody; MGC882 antibody; Yeast APC 11 homolog antibody; Yeast APC11 homolog antibody |
| Raised in | Rabbit |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Human ANAPC11 |
| Immunogen Species | Homo sapiens (Human) |
| Isotype | IgG |
| Purification Method | Antigen Affinity purified |
| Concentration | It differs from different batches. Please contact us to confirm it. |
| Buffer | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Tested Applications | ELISA,WB |
| Protocols | ELISA Protocol Western Blotting(WB) Protocol |
| Troubleshooting and FAQs | Antibody FAQs |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
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| Function |
Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.
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| Gene References into Functions |
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| Subcellular Location | Cytoplasm. Nucleus. |
| Protein Families | RING-box family |
| Tissue Specificity | Expressed at high levels in skeletal muscle and heart; in moderate levels in brain, kidney, and liver; and at low levels in colon, thymus, spleen, small intestine, placenta, lung and peripheral blood leukocyte. |
| Database Links |
HGNC: 14452 OMIM: 614534 KEGG: hsa:51529 UniGene: Hs.534456 |
