ARPC3 Antibody

Datasheet

Code	CSB-PA002128GA01HU
Size	US$685
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Product Details

Uniprot No.	O15145
Target Names	ARPC3
Alternative Names	ARPC3 antibody; ARC21Actin-related protein 2/3 complex subunit 3 antibody; Arp2/3 complex 21 kDa subunit antibody; p21-ARC antibody
Raised in	Rabbit
Species Reactivity	Human,Mouse,Rat
Immunogen	Human ARPC3
Immunogen Species	Homo sapiens (Human)
Isotype	IgG
Purification Method	Antigen Affinity purified
Concentration	It differs from different batches. Please contact us to confirm it.
Buffer	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications	ELISA,WB
Protocols	ELISA Protocol Western Blotting(WB) Protocol
Troubleshooting and FAQs	Antibody FAQs
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time	Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Function (From Uniprot)	Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
Gene References into Functions	Cancer cell motility mediated by the actin-related protein 2/3 complex (Arp2/3) is required for vessel co-option in liver metastases in vivo. PMID: 27748747 genetic association study in population in Canada: Data suggest that an SNP in the promoter region of ARPC3 (CpG-SNP rs3759384 C>T) is associated with metabolic syndrome complicated by severe abdominal obesity and hypertriglyceridemia in the population studied. PMID: 27055012 Endogenous Nogo-B, which may exert its effects through ARPC 2/3 and MYL-9, is necessary for the migration and contraction of airway smooth muscle cells. PMID: 21251247 The actin-related protein 3 structures were more visible with anti-p34Arc monoclonal antibody. PMID: 15793564
Subcellular Location	Cytoplasm, cytoskeleton, Cell projection
Protein Families	ARPC3 family
Database Links	HGNC: 706 OMIM: 604225 KEGG: hsa:10094 STRING: 9606.ENSP00000228825 UniGene: Hs.524741

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