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Code | CSB-PA002128GA01HU |
Size | US$685 How to order? |
Have Questions? | Leave a Message or Start an on-line Chat |
Uniprot No. | O15145 |
Target Names | ARPC3 |
Alternative Names | ARPC3 antibody; ARC21Actin-related protein 2/3 complex subunit 3 antibody; Arp2/3 complex 21 kDa subunit antibody; p21-ARC antibody |
Raised in | Rabbit |
Species Reactivity | Human,Mouse,Rat |
Immunogen | Human ARPC3 |
Immunogen Species | Homo sapiens (Human) |
Isotype | IgG |
Purification Method | Antigen Affinity purified |
Concentration | It differs from different batches. Please contact us to confirm it. |
Buffer | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Tested Applications | ELISA,WB |
Protocols | ELISA Protocol Western Blotting(WB) Protocol |
Troubleshooting and FAQs | Antibody FAQs |
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
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Function |
Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).
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Gene References into Functions |
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Subcellular Location | Cytoplasm, cytoskeleton. Cell projection. Nucleus. |
Protein Families | ARPC3 family |
Database Links |
HGNC: 706 OMIM: 604225 KEGG: hsa:10094 STRING: 9606.ENSP00000228825 UniGene: Hs.524741 |