ARPC3 Antibody

Code CSB-PA002128GA01HU
Size US$685
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Product Details

Uniprot No. O15145
Target Names ARPC3
Alternative Names ARPC3 antibody; ARC21Actin-related protein 2/3 complex subunit 3 antibody; Arp2/3 complex 21 kDa subunit antibody; p21-ARC antibody
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Immunogen Human ARPC3
Immunogen Species Homo sapiens (Human)
Isotype IgG
Purification Method Antigen Affinity purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications ELISA,WB
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Data

Function Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
Gene References into Functions
  1. Cancer cell motility mediated by the actin-related protein 2/3 complex (Arp2/3) is required for vessel co-option in liver metastases in vivo. PMID: 27748747
  2. genetic association study in population in Canada: Data suggest that an SNP in the promoter region of ARPC3 (CpG-SNP rs3759384 C>T) is associated with metabolic syndrome complicated by severe abdominal obesity and hypertriglyceridemia in the population studied. PMID: 27055012
  3. Endogenous Nogo-B, which may exert its effects through ARPC 2/3 and MYL-9, is necessary for the migration and contraction of airway smooth muscle cells. PMID: 21251247
  4. The actin-related protein 3 structures were more visible with anti-p34Arc monoclonal antibody. PMID: 15793564
Subcellular Location Cytoplasm, cytoskeleton, Cell projection
Protein Families ARPC3 family
Database Links

HGNC: 706

OMIM: 604225

KEGG: hsa:10094

STRING: 9606.ENSP00000228825

UniGene: Hs.524741

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