BAG4 Antibody

1. AGS cells overexpressing BAG4 exhibited a significant increase in the percentage of cells in the G1/G0 peak and transfection of shRNA decrese demonstrated the opposite effect. PMID: 29067445
2. acid-induced increase in SODD expression and decrease in cell apoptosis may depend on the activation of NOX5-S and NF-kappaB1 p50 in FLO cells PMID: 27756772
3. SGK1.1 regulates gene transcription upon a different set of genes some of which participate in cell survival pathways (BAG-4) and others in intracellular vesicular traffic (Brox). PMID: 25849655
4. SODD over-expression might be correlated with the clinical classification, curative effect, and prognosis of ALL cells. PMID: 24737427
5. MicroRNA-26a is strongly downregulated in melanoma and induces cell death through repression of silencer of death domains (SODD). PMID: 23190898
6. Altered signaling of TNFalpha-TNFR1 and SODD/BAG4 is responsible for radioresistance in human HT-R15 cells. PMID: 12017295
7. SODD/BAG-4 is not only a silencer of TNFR1 but also a modulator of CD95 activity, regulating the balance of both death-promoting and -depressing signals PMID: 12706861
8. BAG-4 functions as a negative regulator for apobec-1-mediated apoB mRNA editing PMID: 14559896
9. Gene induces transformed phenotype when overexpressed in a cancer breast cell line. PMID: 17178857
10. results of analysis of the genome-wide scan data was a 20 cM region at 8p11-23 in which markers had LODs > or =1.0. Linkage and association analyses of these SNPs yield suggestive results for markers in FGFR1 and BAG4. PMID: 17366557
11. Vincristine induces Jurkat cell apoptosis by downregulating expression of SODD protein and priming the death receptor pathway. PMID: 17605853

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HGNC: 940

OMIM: 603884

KEGG: hsa:9530

STRING: 9606.ENSP00000287322

UniGene: Hs.194726