C6 Antibody, HRP conjugated

Datasheet

Code	CSB-PA004036LB01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) C6 Polyclonal antibody

Uniprot No.

P13671

Target Names

Alternative Names

AW111623 antibody; C6 antibody; CO6_HUMAN antibody; Complement component 6 antibody; Complement component C6 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Complement component C6 protein (521-655AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

HRP

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.

Gene References into Functions

Our study provided novel evidence that genetic variations in complement genes C6 and MASP1were associated with preeclampsia risk, and that the risk varied by preeclampsia subtypes PMID: 27405496
recipient C6 rs9200 polymorphism is associated with HCC recurrence after OLT, and improves the predictive value of clinical models. PMID: 27173880
Structure of complement C6 suggests a mechanism for initiation and unidirectional, sequential assembly of membrane attack complex (MAC). PMID: 22267737
finding of very high serious morbidity in patients with complete C6 deficiency due to meningococcal infections PMID: 22288589
Genetic polymorphisms in C6 gene do not influence the risk of aspirin hypersensitivity in Korean asthmatic patients. PMID: 21704099
produced by trophoblast cells PMID: 19665237
The most common defect, which leads to an increased susceptibility to Neisseria meningitidis infections in the Western Cape, is 879delG. PMID: 17257682

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Involvement in disease

Complement component 6 deficiency (C6D)

Subcellular Location

Secreted.

Protein Families

Complement C6/C7/C8/C9 family

Database Links

HGNC: 1339

OMIM: 217050

KEGG: hsa:729

STRING: 9606.ENSP00000263413

UniGene: Hs.481992

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Service

Phage Display Service

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Related pathways

Complement and coagulation cascades

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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