CACNB1 Antibody

Datasheet

Code	CSB-PA004411DSR2HU
Size	US$166
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Image	Western blot All lanes: CACNB1 antibody at 8.2 μg/ml + Mouse liver tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 66, 58, 54 kDa Observed band size: 66 kDa Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA004411DSR2HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) CACNB1 Polyclonal antibody

Uniprot No.

Q02641

Target Names

CACNB1

Alternative Names

CAB1 antibody; CACB1_HUMAN antibody; CACNB1 antibody; CACNLB1 antibody; Calcium channel L type beta 1 polypeptide antibody; Calcium channel voltage dependent beta 1 subunit antibody; Calcium channel voltage-dependent subunit beta 1 antibody; CCHLB1 antibody; Dihydropyridine sensitive L type calcium channel beta 1 subunit antibody; MGC41896 antibody; Voltage dependent L type calcium channel beta 1 subunit antibody; Voltage-dependent L-type calcium channel subunit beta-1 antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Voltage-dependent L-type calcium channel subunit beta-1 protein (429-598AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Regulatory subunit of L-type calcium channels. Regulates the activity of L-type calcium channels that contain CACNA1A as pore-forming subunit. Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit and increases the presence of the channel complex at the cell membrane. Required for functional expression L-type calcium channels that contain CACNA1D as pore-forming subunit. Regulates the activity of L-type calcium channels that contain CACNA1B as pore-forming subunit.

Gene References into Functions

CACNB1, encoding cardiac L-type calcium channel beta 1 subunit, is a potential target for microRNA-328 in transgenic mice. PMID: 21098446
Data show that the length-dependent mechanism of modulating inactivation kinetics of beta(2) calcium channel subunits can be confirmed and extended to the beta(1) calcium channel subunit. PMID: 19821165

Subcellular Location

Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein.

Protein Families

Calcium channel beta subunit family

Tissue Specificity

Detected in heart ventricle (at protein level). Isoform 1 and isoform 3 are expressed in brain, heart, spleen, central nervous system and neuroblastoma cells. Isoform 2 is expressed in skeletal muscle.

Database Links

HGNC: 1401

OMIM: 114207

KEGG: hsa:782

STRING: 9606.ENSP00000377840

UniGene: Hs.635

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

MAPK signaling pathway Cardiac muscle contraction

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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