CACNG3 Antibody

Code CSB-PA080194
Size US$100
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  • Immunohistochemical analysis of paraffin-embedded Rat Brain Tissue using CACNG3 Polyclonal Antibody.

  • Western blot analysis of 1) Human Brain Tissue, 2) Mouse Brain Tissue, 3) Rat Brain Tissue using CACNG3 Polyclonal Antibody.

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Product Details

Uniprot No.
Target Names
CACNG3
Alternative Names
CACNG3; Voltage-dependent calcium channel gamma-3 subunit; Neuronal voltage-gated calcium channel gamma-3 subunit; Transmembrane AMPAR regulatory protein gamma-3; TARP gamma-3
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic Peptide
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Form
Liquid
Tested Applications
WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-2000
IHC 1:200-500
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Regulates the trafficking to the somatodendritic compartment and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.
Gene References into Functions
  1. These results suggest that CACNG3 is the best candidate for an age-related macular degeneration risk gene within the 16p12 linkage peak. PMID: 21169531
  2. examined distribution of the stargazin-like proteins gamma2, gamma3, and gamma4 in human CNS: gamma2 is expressed in cerebellum, cerebral cortex, hippocampus and thalamus, whereas gamma3 abounds in cerebral cortex & amygdala and gamma4 in basal ganglia PMID: 14505496
  3. CACNG3 on chromosome 16p12-p13.1 may represent susceptibility loci for CAE. PMID: 17264864
Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
PMP-22/EMP/MP20 family, CACNG subfamily
Database Links

HGNC: 1407

OMIM: 606403

KEGG: hsa:10368

STRING: 9606.ENSP00000005284

UniGene: Hs.7235

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