CAMK2N1 Antibody, Biotin conjugated

Code CSB-PA004469ND01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CAMK2N1 Polyclonal antibody
Uniprot No.
Target Names
CAMK2N1
Alternative Names
CAMK2N1Calcium/calmodulin-dependent protein kinase II inhibitor 1 antibody; CaMKII inhibitory protein alpha antibody; CaMKIIN-alpha antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Peptide sequence from Human Calcium/calmodulin-dependent protein kinase II inhibitor 1 protein (9-27AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Potent and specific inhibitor of CaM-kinase II (CAMK2).
Gene References into Functions
  1. CAMK2N1 expression is significantly downregulated in human masticatory mucosa during wound healing PMID: 28005267
  2. Hypermethylation of RUNX3/CAMK2N1 is associated with poor clinical outcome in Type II EOC, also after macroscopic complete resection. PMID: 26175272
  3. contributes to prostate cancer growth and survival through androgen receptor-dependent signaling PMID: 25296973
  4. Analyses suggest that CAMK2N1 plays a tumor suppressive role in prostate cancer cells. Reduced CAMK2N1 expression correlates to human prostate cancer progression and predicts poor clinical outcome. PMID: 25003983
  5. hCaMKIINalpha suppresses tumor growth by inducing cell cycle arrest via p27 stabilization PMID: 18305109

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Subcellular Location
Cell junction, synapse, synaptosome. Cell junction, synapse, postsynaptic density.
Protein Families
CAMK2N family
Tissue Specificity
Widely expressed. Nor detected in skeletal muscle.
Database Links

HGNC: 24190

OMIM: 614986

KEGG: hsa:55450

UniGene: Hs.731383

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