CAMK2N1 Antibody

Datasheet

Code	CSB-PA004469NA01HU
Size	US$166
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Image	Immunofluorescence staining of HepG2 cells with CSB-PA004469NA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) CAMK2N1 Polyclonal antibody

Uniprot No.

Q7Z7J9

Target Names

CAMK2N1

Alternative Names

CAMK2N1Calcium/calmodulin-dependent protein kinase II inhibitor 1 antibody; CaMKII inhibitory protein alpha antibody; CaMKIIN-alpha antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Peptide sequence from Human Calcium/calmodulin-dependent protein kinase II inhibitor 1 protein (9-27AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The CAMK2N1 Antibody (Product code: CSB-PA004469NA01HU) is Non-conjugated. For CAMK2N1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA004469NB01HU	CAMK2N1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA004469NC01HU	CAMK2N1 Antibody, FITC conjugated
Biotin	CSB-PA004469ND01HU	CAMK2N1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IF

Recommended Dilution

Application	Recommended Dilution
IF	1:50-1:200

Protocols

ELISA Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Potent and specific inhibitor of CaM-kinase II (CAMK2).

Gene References into Functions

CAMK2N1 expression is significantly downregulated in human masticatory mucosa during wound healing PMID: 28005267
Hypermethylation of RUNX3/CAMK2N1 is associated with poor clinical outcome in Type II EOC, also after macroscopic complete resection. PMID: 26175272
contributes to prostate cancer growth and survival through androgen receptor-dependent signaling PMID: 25296973
Analyses suggest that CAMK2N1 plays a tumor suppressive role in prostate cancer cells. Reduced CAMK2N1 expression correlates to human prostate cancer progression and predicts poor clinical outcome. PMID: 25003983
hCaMKIINalpha suppresses tumor growth by inducing cell cycle arrest via p27 stabilization PMID: 18305109

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Subcellular Location

Cell junction, synapse, synaptosome. Cell junction, synapse, postsynaptic density.

Protein Families

CAMK2N family

Tissue Specificity

Widely expressed. Nor detected in skeletal muscle.

Database Links

HGNC: 24190

OMIM: 614986

KEGG: hsa:55450

UniGene: Hs.731383

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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