CCHCR1 Antibody

Datasheet

Code	CSB-PA004769ESR1HU
Size	US$166
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Image	Western blot All lanes: CCHCR1 antibody at 2.67 μg/ml + 293T whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 89, 100, 96 kDa Observed band size: 89 kDa Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA004769ESR1HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) CCHCR1 Polyclonal antibody

Uniprot No.

Q8TD31

Target Names

CCHCR1

Alternative Names

CCHCR1 antibody; C6orf18 antibody; HCR antibody; Coiled-coil alpha-helical rod protein 1 antibody; Alpha-helical coiled-coil rod protein antibody; Putative gene 8 protein antibody; Pg8 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Coiled-coil alpha-helical rod protein 1 protein (483-782AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

May be a regulator of keratinocyte proliferation or differentiation.

Gene References into Functions

psoriasis candidate gene CCHCR1 expressed at P-bodies and centrosomes PMID: 29866042
CCHCR1 interacts specifically with the E2 protein of human papillomavirus type 16 on a surface overlapping BRD4 binding PMID: 24664238
Confocal imaging confirmed the localization of CCHCR1 in P-bodies. PMID: 24858563
The centrosomal localization of CCHCR1 provides a connection to the abnormal cell proliferation and offers a link to possible cellular pathways altered in psoriasis. PMID: 23189171
Psoriasis is associated with genetic polymorphism in the CCHCR1 gene and in a genomic segment flanking the HLA-C region in the North Indian population. PMID: 22182809
Isolated by a two hybrid assay, StAR binding protein binds StAR protein in cells and enhances the ability of StAR protein to promote syntheses of steroid hormones.(sTAR binding protein) PMID: 12909641
These studies show that miR-122, a 22-nucleotide microRNA, is derived from a liver-specific noncoding polyadenylated RNA transcribed from the gene hcr. PMID: 17179747
These results suggest a role for CCHCR1 in the pathogenesis of psoriasis via the regulation of skin steroid metabolism. PMID: 17221218
Results show that HLA-Cw6 and CCHCR1 risk allele associations with clinical features of psoriasis are predictably highly similar in a Finnish nationwide cohort of 379 psoriasis patients. PMID: 17340018
the aberrant function of CCHCR1 may lead to abnormal keratinocyte proliferation which is a key feature of psoriatic epidermis. PMID: 18174193
CCHCR1 is up-regulated in skin cancer and associated with EGFR expression PMID: 19551138

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Subcellular Location

Cytoplasm. Nucleus.

Tissue Specificity

Found in all tissues tested, abundantly expressed in heart, liver, skeletal muscle, kidney and pancreas, and to a lesser extent in lung and placenta. Overexpressed in keratinocytes of psoriatic lesions.

Database Links

HGNC: 13930

OMIM: 605310

KEGG: hsa:54535

STRING: 9606.ENSP00000379566

UniGene: Hs.485075

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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