CDH15 Antibody

Code CSB-PA005040LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: Rat heart tissue
    All lanes: CDH15 antibody at 3.2μg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 89 kDa
    Observed band size: 89 kDa

  • Immunofluorescence staining of HepG2 cells with CSB-PA005040LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CDH15 Polyclonal antibody
Uniprot No.
Target Names
CDH15
Alternative Names
CDH15; CDH14; CDH3; Cadherin-15; Cadherin-14; Muscle cadherin; M-cadherin
Raised in
Rabbit
Species Reactivity
Human, Rat
Immunogen
Recombinant Human Cadherin-15 protein (639-766AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The CDH15 Antibody (Product code: CSB-PA005040LA01HU) is Non-conjugated. For CDH15 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA005040LB01HU CDH15 Antibody, HRP conjugated ELISA
FITC CSB-PA005040LC01HU CDH15 Antibody, FITC conjugated
Biotin CSB-PA005040LD01HU CDH15 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. M-cadherin is part of the myogenic program and may provide a trigger for terminal muscle differentiation.
Gene References into Functions
  1. The cell adhesion molecule M-cadherin is not essential for muscle development and regeneration. PMID: 12052883
  2. Alterations in CDH15 in patients with mild to severe intellectual disability are reported. PMID: 19012874
Involvement in disease
Mental retardation, autosomal dominant 3 (MRD3)
Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Tissue Specificity
Expressed in the brain and cerebellum.
Database Links

HGNC: 1754

OMIM: 114019

KEGG: hsa:1013

STRING: 9606.ENSP00000289746

UniGene: Hs.148090

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