CDH15 Antibody

Code CSB-PA276016
Size US$297
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  • Western blot analysis of extracts from HepG2 cells and 293 cells, using CDH15 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CDH15 Polyclonal antibody
Uniprot No.
Target Names
CDH15
Alternative Names
CDH15; CDH14; CDH3; Cadherin-15; Cadherin-14; Muscle cadherin; M-cadherin
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from internal of Human CDH15.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. M-cadherin is part of the myogenic program and may provide a trigger for terminal muscle differentiation.
Gene References into Functions
  1. The cell adhesion molecule M-cadherin is not essential for muscle development and regeneration. PMID: 12052883
  2. Alterations in CDH15 in patients with mild to severe intellectual disability are reported. PMID: 19012874
Involvement in disease
Mental retardation, autosomal dominant 3 (MRD3)
Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Tissue Specificity
Expressed in the brain and cerebellum.
Database Links

HGNC: 1754

OMIM: 114019

KEGG: hsa:1013

STRING: 9606.ENSP00000289746

UniGene: Hs.148090

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