COLEC10 Antibody, HRP conjugated

Code CSB-PA896556LB01HU
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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) COLEC10 Polyclonal antibody
Uniprot No. Q9Y6Z7
Target Names COLEC10
Alternative Names CL-34 antibody; CL-L1 antibody; CLL1 antibody; COL10_HUMAN antibody; Colec10 antibody; Collectin liver 1 antibody; Collectin liver protein 1 antibody; Collectin sub family member 10 (C-type lectin) antibody; Collectin sub family member 10 antibody; Collectin subfamily member 10 antibody; Collectin-10 antibody; Collectin-34 antibody; MGC118794 antibody; MGC118795 antibody; OTTHUMP00000228058 antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Collectin-10 protein (28-277AA)
Immunogen Species Homo sapiens (Human)
Conjugate HRP
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form Liquid
Tested Applications ELISA
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Lectin that binds to various sugars: galactose > mannose = fucose > N-acetylglucosamine > N-acetylgalactosamine. Acts as a chemoattractant, probably involved in the regulation of cell migration.
Gene References into Functions
  1. High CLL1 expression is associated with cardiovascular disease. PMID: 27341702
  2. Exome sequencing reveals mutations in collectin sub-family member 10 (C-type lectin) protein (COLEC10) as a cause of 3MC syndrome with main features include facial dysmorphism, craniosynostosis and cleft lip/palate. PMID: 28301481
  3. high serum CL-L1 concentration in critically ill children upon PICU admission is associated with an increased risk of infection and prolonged need of intensive care, and counteracts the protective effect of having a high MASP-3 concentration PMID: 27057739
  4. Data indicate differences in the plasma concentrations of collectin liver 1 and collectin kidney 1, M-ficolin and H-ficol in systemic lupus erythematosus (SLE) patients compared to a group of healthy controls. PMID: 26154564
  5. Carriers of COLEC10 Arg125Trp had increased CL-L1 serum levels. PMID: 25710878
  6. Most plasma CL-K1 was found in complex with CL-L1 in a ratio suggesting a heteromeric subunit of 1 CL-L1 & 2 CL-K1 polypeptides. PMID: 24174618

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Involvement in disease 3MC syndrome 3 (3MC3)
Subcellular Location Secreted. Golgi apparatus. Cytoplasm.
Protein Families COLEC10/COLEC11 family
Tissue Specificity Highly expressed in liver, placenta and adrenal gland. Moderately expressed in small intestine, lung, stomach and prostate. Weakly expressed in trachea and spleen.
Database Links

HGNC: 2220

OMIM: 248340

KEGG: hsa:10584

STRING: 9606.ENSP00000332723

UniGene: Hs.176615

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