CPN1 Antibody

Datasheet

Code	CSB-PA005898ESR2HU
Size	US$166
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Image	Western blot All lanes: CPN1 antibody at 6.19µg/ml Lane 1: Mouse liver tissue Lane 2: MCF-7 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 52 kDa Observed band size: 52 kDa Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA005898ESR2HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA005898ESR2HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) CPN1 Polyclonal antibody

Uniprot No.

P15169

Target Names

CPN1

Alternative Names

ACBP antibody; Anaphylatoxin inactivator antibody; Arginine carboxypeptidase antibody; Carboxypeptidase N catalytic chain antibody; Carboxypeptidase N polypeptide 1 50 kD antibody; Carboxypeptidase N polypeptide 1 antibody; Carboxypeptidase N small subunit antibody; Carboxypeptidase N subunit 1 antibody; CBPN_HUMAN antibody; CPN antibody; CPN1 antibody; Kininase 1 antibody; Kininase-1 antibody; Kininase1 antibody; Lysine carboxypeptidase antibody; Plasma carboxypeptidase B antibody; SCPN antibody; Serum carboxypeptidase N antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Carboxypeptidase N catalytic chain protein (209-458AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Protects the body from potent vasoactive and inflammatory peptides containing C-terminal Arg or Lys (such as kinins or anaphylatoxins) which are released into the circulation.

Gene References into Functions

CPN binds to fibrinogen and is present in a fibrin clot prepared from plasma. PMID: 23000409
carboxypeptidase N regulates the biologic activity of SDF-1alpha by reducing the chemokine-specific activity PMID: 15718415
This review summarizes the structure, enzymatic properties and function of this enzyme, including insights gained by the recent elucidation of the crystal structure of the CPN catalytic subunit and structural modeling of the non-catalytic 83 kDa subunit. PMID: 18039526

Involvement in disease

Carboxypeptidase N deficiency (CPND)

Subcellular Location

Secreted, extracellular space.

Protein Families

Peptidase M14 family

Tissue Specificity

Synthesized in the liver and secreted in plasma.

Database Links

HGNC: 2312

OMIM: 212070

KEGG: hsa:1369

STRING: 9606.ENSP00000359446

UniGene: Hs.2246

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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