CPN1 Antibody

Datasheet

Code	CSB-PA447827
Size	US$297
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Image	Western blot analysis of extracts from RAW264.7 cells, using CPN1 antibody.
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) CPN1 Polyclonal antibody

Uniprot No.

P15169

Target Names

CPN1

Alternative Names

ACBP antibody; Anaphylatoxin inactivator antibody; Arginine carboxypeptidase antibody; Carboxypeptidase N catalytic chain antibody; Carboxypeptidase N polypeptide 1 50 kD antibody; Carboxypeptidase N polypeptide 1 antibody; Carboxypeptidase N small subunit antibody; Carboxypeptidase N subunit 1 antibody; CBPN_HUMAN antibody; CPN antibody; CPN1 antibody; Kininase 1 antibody; Kininase-1 antibody; Kininase1 antibody; Lysine carboxypeptidase antibody; Plasma carboxypeptidase B antibody; SCPN antibody; Serum carboxypeptidase N antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthesized peptide derived from C-terminal of Human CPN1.

Immunogen Species

Homo sapiens (Human)

Clonality

Polyclonal

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Tested Applications

ELISA,WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:3000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Protects the body from potent vasoactive and inflammatory peptides containing C-terminal Arg or Lys (such as kinins or anaphylatoxins) which are released into the circulation.

Gene References into Functions

CPN binds to fibrinogen and is present in a fibrin clot prepared from plasma. PMID: 23000409
carboxypeptidase N regulates the biologic activity of SDF-1alpha by reducing the chemokine-specific activity PMID: 15718415
This review summarizes the structure, enzymatic properties and function of this enzyme, including insights gained by the recent elucidation of the crystal structure of the CPN catalytic subunit and structural modeling of the non-catalytic 83 kDa subunit. PMID: 18039526

Involvement in disease

Carboxypeptidase N deficiency (CPND)

Subcellular Location

Secreted, extracellular space.

Protein Families

Peptidase M14 family

Tissue Specificity

Synthesized in the liver and secreted in plasma.

Database Links

HGNC: 2312

OMIM: 212070

KEGG: hsa:1369

STRING: 9606.ENSP00000359446

UniGene: Hs.2246

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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