CTSF Antibody

Code CSB-PA15279A0Rb
Size US$166
Order now
The Latest Promotion Free Antibody trial simple
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CTSF Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
AI481912 antibody; CATF_HUMAN antibody; Cathepsin F antibody; CathepsinF antibody; CATSF antibody; CLN13 antibody; Ctsf antibody; EC 3.4.22.41 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Cathepsin F protein (273-484AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The CTSF Antibody (Product code: CSB-PA15279A0Rb) is Non-conjugated. For CTSF Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA15279B0Rb CTSF Antibody, HRP conjugated ELISA
FITC CSB-PA15279C0Rb CTSF Antibody, FITC conjugated
Biotin CSB-PA15279D0Rb CTSF Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
Gene References into Functions
  1. The CTSF gene may function as a tumor suppressor in gastric cancer PMID: 28474574
  2. Biallelic mutations in this gene have been shown to cause Type B Kufs disease, an adult-onset neuronal ceroid lipofuscinosis with some cases resembling the impairment seen in AD. PMID: 27524508
  3. Disease-causing cathepsin-F mutants fail to cleave LIMP-2. Our findings provide evidence that LIMP-2 represents an in vivo substrate of cathepsin-F with relevance for understanding the pathophysiology of type-B-Kufs-disease. PMID: 25576872
  4. Small hairpin RNA silencing of proteinases overexpressed in diabetic corneas enhanced corneal epithelial and stem cell marker staining and accelerated wound healing. PMID: 24255036
  5. Homozygous and compound heterozygous missense mutations in CTSF are associated with adult-onset neuronal ceroid lipofuscinosis. PMID: 23297359
  6. cathepsin F has a role in modifying low density lipoprotein particles PMID: 15184381
  7. cathepsin F, matrix metalloproteinases 11 and 12 are upregulated in cervical cancer PMID: 15989693
  8. data demonstrate a novel proatherogenic role for AngII, namely its ability to enhance secretion of lysosomal cathepsin F by monocyte-derived macrophages PMID: 16963053

Show More

Hide All

Involvement in disease
Ceroid lipofuscinosis, neuronal, 13 (CLN13)
Subcellular Location
Lysosome.
Protein Families
Peptidase C1 family
Tissue Specificity
High expression levels in heart, skeletal muscle, brain, testis and ovary; moderate levels in prostate, placenta, liver and colon; and no detectable expression in peripheral leukocytes and thymus.
Database Links

HGNC: 2531

OMIM: 603539

KEGG: hsa:8722

STRING: 9606.ENSP00000310832

UniGene: Hs.11590

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
Place an order now

I. Product details

*
*
*
*

II. Contact details

*
*

III. Ship To

*
*
*
*
*
*
*

IV. Bill To

*
*
*
*
*
*
*
*