Ccl12 Antibody

Datasheet

Code	CSB-PA09139A0Rb
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Mus musculus (Mouse) Ccl12 Polyclonal antibody

Uniprot No.

Q62401

Target Names

Ccl12

Alternative Names

C-C motif chemokine 12 antibody; Ccl12 antibody; CCL12_MOUSE antibody; Macrophage/monocyte Chemotactic Protein antibody; MCP-1-related chemokine antibody; MCP-5 antibody; Monocyte chemoattractant protein 5 antibody; Monocyte chemotactic protein 5 antibody; OTTMUSP00000000792 antibody; Scya12 antibody; Small inducible cytokine A12 antibody; Small-inducible cytokine A12 antibody

Raised in

Rabbit

Species Reactivity

Mouse

Immunogen

Recombinant Mouse C-C motif chemokine 12 ptotein (23-104AA)

Immunogen Species

Mus musculus (Mouse)

Conjugate

Non-conjugated

The Ccl12 Antibody (Product code: CSB-PA09139A0Rb) is Non-conjugated. For Ccl12 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA09139B0Rb	Ccl12 Antibody, HRP conjugated	ELISA
FITC	CSB-PA09139C0Rb	Ccl12 Antibody, FITC conjugated
Biotin	CSB-PA09139D0Rb	Ccl12 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Chemotactic factor that attracts eosinophils, monocytes, and lymphocytes but not neutrophils. Potent monocyte active chemokine that signals through CCR2. Involved in allergic inflammation and the host response to pathogens and may play a pivotal role during early stages of allergic lung inflammation.

Gene References into Functions

After 100% O2 treatment, genes involved in inflammation (Ccl12), angiogenesis (Igfr1, Stat3), and metabolism (Hk2) were upregulated. PMID: 24458145
Data indicate mRNA upregulation of CCR2 and CCR2 ligands CCL2, CCL7, CCL8, and CCL12 in aortas from DOCA/salt-treated hypertension. PMID: 23033370
The transforming growth factor (TGF)beta type II receptor/MCP-5 axis is an essential crossroad for joint development and endochondral growth. PMID: 22814601
CCL12 proteins were present in the vast majority of tissues investigated. mRNA for these proteins was also expressed in most of these tissues suggesting local production and the ability to respond in situ to inflammatory stimuli. PMID: 20931267

Subcellular Location

Secreted.

Protein Families

Intercrine beta (chemokine CC) family

Tissue Specificity

Predominantly expressed in the lymph nodes and thymus. Also found in the salivary glands containing lymph nodes, breast, heart, lung, brain, small intestine, kidney and colon.

Database Links

KEGG: mmu:20293

STRING: 10090.ENSMUSP00000000194

UniGene: Mm.867

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The Overview of Chemokine Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Target Therapy

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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