Ccl12 Antibody

Code CSB-PA09139A0Rb
Size US$166
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Product Details

Full Product Name
Rabbit anti-Mus musculus (Mouse) Ccl12 Polyclonal antibody
Uniprot No.
Target Names
Ccl12
Alternative Names
C-C motif chemokine 12 antibody; Ccl12 antibody; CCL12_MOUSE antibody; Macrophage/monocyte Chemotactic Protein antibody; MCP-1-related chemokine antibody; MCP-5 antibody; Monocyte chemoattractant protein 5 antibody; Monocyte chemotactic protein 5 antibody; OTTMUSP00000000792 antibody; Scya12 antibody; Small inducible cytokine A12 antibody; Small-inducible cytokine A12 antibody
Raised in
Rabbit
Species Reactivity
Mouse
Immunogen
Recombinant Mouse C-C motif chemokine 12 ptotein (23-104AA)
Immunogen Species
Mus musculus (Mouse)
Conjugate
Non-conjugated

The Ccl12 Antibody (Product code: CSB-PA09139A0Rb) is Non-conjugated. For Ccl12 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA09139B0Rb Ccl12 Antibody, HRP conjugated ELISA
FITC CSB-PA09139C0Rb Ccl12 Antibody, FITC conjugated
Biotin CSB-PA09139D0Rb Ccl12 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Chemotactic factor that attracts eosinophils, monocytes, and lymphocytes but not neutrophils. Potent monocyte active chemokine that signals through CCR2. Involved in allergic inflammation and the host response to pathogens and may play a pivotal role during early stages of allergic lung inflammation.
Gene References into Functions
  1. After 100% O2 treatment, genes involved in inflammation (Ccl12), angiogenesis (Igfr1, Stat3), and metabolism (Hk2) were upregulated. PMID: 24458145
  2. Data indicate mRNA upregulation of CCR2 and CCR2 ligands CCL2, CCL7, CCL8, and CCL12 in aortas from DOCA/salt-treated hypertension. PMID: 23033370
  3. The transforming growth factor (TGF)beta type II receptor/MCP-5 axis is an essential crossroad for joint development and endochondral growth. PMID: 22814601
  4. CCL12 proteins were present in the vast majority of tissues investigated. mRNA for these proteins was also expressed in most of these tissues suggesting local production and the ability to respond in situ to inflammatory stimuli. PMID: 20931267
Subcellular Location
Secreted.
Protein Families
Intercrine beta (chemokine CC) family
Tissue Specificity
Predominantly expressed in the lymph nodes and thymus. Also found in the salivary glands containing lymph nodes, breast, heart, lung, brain, small intestine, kidney and colon.
Database Links

KEGG: mmu:20293

STRING: 10090.ENSMUSP00000000194

UniGene: Mm.867

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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