Ccl4 Antibody

Datasheet

Code	CSB-PA09069A0Rb
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA09069A0Rb at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Mouse Ccl4 Polyclonal antibody

Uniprot No.

P14097

Target Names

Ccl4

Alternative Names

Ccl4 antibody; Mip1b antibody; Scya4 antibody; C-C motif chemokine 4 antibody; Immune activation protein 2 antibody; ACT-2 antibody; ACT2 antibody; Macrophage inflammatory protein 1-beta antibody; MIP-1-beta antibody; Protein H400 antibody; SIS-gamma antibody; Small-inducible cytokine A4 antibody

Raised in

Rabbit

Species Reactivity

Mouse

Immunogen

Recombinant Mouse C-C motif chemokine 4 protein (24-92AA)

Immunogen Species

Mouse

Conjugate

Non-conjugated

The Ccl4 Antibody (Product code: CSB-PA09069A0Rb) is Non-conjugated. For Ccl4 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA09069B0Rb	Ccl4 Antibody, HRP conjugated	ELISA
FITC	CSB-PA09069C0Rb	Ccl4 Antibody, FITC conjugated
Biotin	CSB-PA09069D0Rb	Ccl4 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.1mol/L NaCl, 15mmol/L NaN3, PH7.2

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Monokine with inflammatory and chemokinetic properties.

Gene References into Functions

CCL4-CCR5 axis can contribute to breast cancer metastasis to bone by mediating the interaction between cancer cells and fibroblasts in bone cavity. PMID: 27177471
YY1 regulates lung CCL4 transcription in pulmonary tuberculosis. PMID: 26786659
Ccl4 mRNAs increased within 5 h after injury in mouse cortical slices. PMID: 25895671
CCL4 and CCL5 expression was higher in livers of infected WSX-1(-/-) mice than infected WT mice, and hepatic CD4 T cells from WSX-1(-/-) mice expressed higher levels of CCR5 than cells from WT mice PMID: 24244314
CCL4 upregulation was associated with increased Snail expression and downregulation of p53/PTEN in high-grade PIN and prostate cancer PMID: 23878190
These results suggest that MIP-1beta is a novel key mediator, and the peripheral MIP-1beta-CCR5 axis contributes to neuropathic pain. PMID: 22528550
results indicate that MIP-1beta is involved in the recruitment of bone marrow-derived monocyte lineage cells PMID: 21912378
increased responsiveness of murine eosinophils to MIP-1beta is mediated by CCR5 receptor in mice PMID: 12050188
macrophage inflammatory protein-1beta is a hypoxia-induced neutrophil survival factor. PMID: 15630139
MIP-1beta is overexpressed, and VE-cadherin is underexpressed in heart transplant allografts compared with isografts PMID: 15897346
Overproduction of MIP-1beta in chemokine (C-C motif) receptor 5-deficient mice after collagen II-immunization may contribute partially to the occurrence of arthritis PMID: 15967376
The expression and role CXCL12 and CCL4 and their receptors (CXCR4 and CCR5) in regulating thymocyte migration in conjunction with extracellular matrix during acute T. cruzi infection are investigated. PMID: 16637021
ATF3 appears to be part of a control mechanism that limits the amount of CCL4 released by macrophages, preventing excessive inflammation. PMID: 16982098
Antibody neutralization of CCL4 abrogates the ability of T-cells from IL-4-treated NOD mice to transfer protection against type 1 diabetes. PMID: 17327452

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Subcellular Location

Secreted.

Protein Families

Intercrine beta (chemokine CC) family

Database Links

KEGG: mmu:20303

STRING: 10090.ENSMUSP00000019074

UniGene: Mm.244263

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Protein Service

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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