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Ccl4 Antibody

Datasheet
Code CSB-PA09069A0Rb
Size US$166
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  • Immunohistochemistry(IHC) 1- Ccl4 Antibody
    Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA09069A0Rb at dilution of 1:100
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Product Details

Full Product Name
Rabbit anti-Mouse Ccl4 Polyclonal antibody
Uniprot No.
P14097
Target Names
Ccl4
Alternative Names
Ccl4 antibody; Mip1b antibody; Scya4 antibody; C-C motif chemokine 4 antibody; Immune activation protein 2 antibody; ACT-2 antibody; ACT2 antibody; Macrophage inflammatory protein 1-beta antibody; MIP-1-beta antibody; Protein H400 antibody; SIS-gamma antibody; Small-inducible cytokine A4 antibody
Raised in
Rabbit
Species Reactivity
Mouse
Immunogen
Recombinant Mouse C-C motif chemokine 4 protein (24-92AA)
Immunogen Species
Mouse
Conjugate
Non-conjugated

The Ccl4 Antibody (Product code: CSB-PA09069A0Rb) is Non-conjugated. For Ccl4 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA09069B0Rb Ccl4 Antibody, HRP conjugated ELISA
FITC CSB-PA09069C0Rb Ccl4 Antibody, FITC conjugated
Biotin CSB-PA09069D0Rb Ccl4 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.1mol/L NaCl, 15mmol/L NaN3, PH7.2
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Protocols
ELISA Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Related Products

Ccl4 Proteins

Ccl4 ELISA kits

Customer Reviews and Q&A

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Target Background

Function
Monokine with inflammatory and chemokinetic properties.
Gene References into Functions
  1. CCL4-CCR5 axis can contribute to breast cancer metastasis to bone by mediating the interaction between cancer cells and fibroblasts in bone cavity. PMID: 27177471
  2. YY1 regulates lung CCL4 transcription in pulmonary tuberculosis. PMID: 26786659
  3. Ccl4 mRNAs increased within 5 h after injury in mouse cortical slices. PMID: 25895671
  4. CCL4 and CCL5 expression was higher in livers of infected WSX-1(-/-) mice than infected WT mice, and hepatic CD4 T cells from WSX-1(-/-) mice expressed higher levels of CCR5 than cells from WT mice PMID: 24244314
  5. CCL4 upregulation was associated with increased Snail expression and downregulation of p53/PTEN in high-grade PIN and prostate cancer PMID: 23878190
  6. These results suggest that MIP-1beta is a novel key mediator, and the peripheral MIP-1beta-CCR5 axis contributes to neuropathic pain. PMID: 22528550
  7. results indicate that MIP-1beta is involved in the recruitment of bone marrow-derived monocyte lineage cells PMID: 21912378
  8. increased responsiveness of murine eosinophils to MIP-1beta is mediated by CCR5 receptor in mice PMID: 12050188
  9. macrophage inflammatory protein-1beta is a hypoxia-induced neutrophil survival factor. PMID: 15630139
  10. MIP-1beta is overexpressed, and VE-cadherin is underexpressed in heart transplant allografts compared with isografts PMID: 15897346
  11. Overproduction of MIP-1beta in chemokine (C-C motif) receptor 5-deficient mice after collagen II-immunization may contribute partially to the occurrence of arthritis PMID: 15967376
  12. The expression and role CXCL12 and CCL4 and their receptors (CXCR4 and CCR5) in regulating thymocyte migration in conjunction with extracellular matrix during acute T. cruzi infection are investigated. PMID: 16637021
  13. ATF3 appears to be part of a control mechanism that limits the amount of CCL4 released by macrophages, preventing excessive inflammation. PMID: 16982098
  14. Antibody neutralization of CCL4 abrogates the ability of T-cells from IL-4-treated NOD mice to transfer protection against type 1 diabetes. PMID: 17327452

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Subcellular Location
Secreted.
Protein Families
Intercrine beta (chemokine CC) family
Database Links
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