DCTN3 Antibody

Code CSB-PA210409
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA210409(DCTN3 Antibody) at dilution 1/70, on the right is treated with fusion protein. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA210409(DCTN3 Antibody) at dilution 1/70, on the right is treated with fusion protein. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
DCTN3
Alternative Names
DCNT22 antibody; DCTN 22 antibody; DCTN22 antibody; Dctn3 antibody; DCTN3_HUMAN antibody; dynactin 3 (p22) antibody; dynactin 3 antibody; dynactin 3 isoform 1 antibody; Dynactin complex subunit 22 kDa subunit antibody; dynactin light chain antibody; Dynactin subunit 3 antibody; p22 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Fusion protein of Human DCTN3
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:10000
IHC 1:100-1:300
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Together with dynein may be involved in spindle assembly and cytokinesis.
Gene References into Functions
  1. Study found that in peripheral blood mononuclear cells the median expression of KIFC3, KIF1B, and KIF5C was much lower than the expression of dynactin subunits DCTN1 and DCTN3, in both sporadic amyotrophic lateral sclerosis and healthy cases PMID: 26954557
Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Cleavage furrow. Midbody. Note=Localizes to punctate cytoplasmic structures and to the centrosome during interphase, and to kinetochores and to spindle poles throughout mitosis. Colocalizes with dynein to the cleavage furrow and to midbody of dividing cells.
Protein Families
Dynactin subunit 3 family
Tissue Specificity
Ubiquitously expressed. Highly expressed in muscle and pancreas and detected at lower levels in brain.
Database Links

HGNC: 2713

OMIM: 607387

KEGG: hsa:11258

STRING: 9606.ENSP00000259632

UniGene: Hs.511768

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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