DUSP9 Antibody, Biotin conjugated

Code CSB-PA859528LD01HU
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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) DUSP9 Polyclonal antibody
Uniprot No. Q99956
Target Names DUSP9
Alternative Names Dual specificity phosphatase 9 antibody; Dual specificity protein phosphatase 9 antibody; DUS9_HUMAN antibody; DUSP9 antibody; MAP kinase phosphatase 4 antibody; Mitogen activated protein kinase phosphatase 4 antibody; Mitogen-activated protein kinase phosphatase 4 antibody; MKP 4 antibody; MKP-4 antibody; MKP4 antibody; serine/threonine specific protein phosphatase antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Dual specificity protein phosphatase 9 protein (142-263AA)
Immunogen Species Homo sapiens (Human)
Conjugate Biotin
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Inactivates MAP kinases. Has a specificity for the ERK family.
Gene References into Functions
  1. The results of this study, combined with previous studies, suggested that therapeutic intervention to increase the expression or activity of DUSP9 may enable the activation of anti-proliferation signals in malignant cells. PMID: 25998184
  2. A possible use for DUSP9 as CIMP marker. PMID: 24838152
  3. DUSP9 protein levels were markedly suppressed in severe pre-eclampsia, but not in severe IUGR. This suppression might be attributable to the prolonged hypoxic conditions found in pre-eclampsia. PMID: 23276385
  4. The DUSP9 locus is a common susceptibility locus for type 2 diabetes across different ethnicities, and 6 loci identified in South Asian genome-wide association studies also have significant effect on susceptibility to Japanese type 2 diabetes. PMID: 23029454
  5. decreased expression of DUSP-9 is associated with poor prognosis in ccRCC. PMID: 21943117
  6. 2.7 A resolution crystal structure of the catalytic domain of MKP-4 (MKP-4C) is presented PMID: 21206059
  7. microtubule disruption by MKP4 provides a novel mechanism for tumor suppression by a cytosolic MKP PMID: 18006813

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Subcellular Location Cytoplasm.
Protein Families Protein-tyrosine phosphatase family, Non-receptor class dual specificity subfamily
Database Links

HGNC: 3076

OMIM: 300134

KEGG: hsa:1852

STRING: 9606.ENSP00000345853

UniGene: Hs.144879

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