EGFL6 Antibody

Code CSB-PA138359
Size US$166
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  • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal brain tissue, Primary antibody: CSB-PA138359(EGFL6 Antibody) at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
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Product Details

Uniprot No.
Target Names
EGFL6
Alternative Names
EGF like domain multiple 6 antibody; EGF repeat containing protein 6 antibody; EGF-like protein 6 antibody; EGF-like-domain multiple 6 antibody; egfl6 antibody; EGFL6_HUMAN antibody; epidermal growth factor like protein 6 antibody; Epidermal growth factor-like protein 6 antibody; MAEG antibody; MAM and EGF domain containing antibody; MAM and EGF domains containing gene protein antibody; MAM and EGF domains-containing gene protein antibody; W80 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Fusion protein of Human EGFL6
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:2000
WB 1:200-1:1000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly.
Gene References into Functions
  1. In conclusion, our results suggest that plasma level of EGFL6 may be useful to assess disease progression, and especially advanced T status and higher TNM stage in patients with oral squamous cell carcinoma. PMID: 28539817
  2. EGFL6 is an angiocrine and tumor cell factor that promotes tumorigenesis via SHP2-mediated signaling. EGFL6 stimulates ALDH+ ovarian cancer stem cell to migrate and undergo asymmetric division. PMID: 27803106
  3. EGFL6 was overexpressed in benign meningioma tissues and serum. PMID: 23285163
  4. results indicate that human EGFL6 is a paracrine/autocrine growth factor of adipose tissue up-regulated in obesity and potentially involved in the process of adipose tissue expansion and the development of obesity PMID: 20574786
  5. There is an absence of GNAS and EGFL6 mutations in common human cancers. PMID: 18038328

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Subcellular Location
Secreted, extracellular space, extracellular matrix, basement membrane.
Protein Families
Nephronectin family
Database Links

HGNC: 3235

OMIM: 300239

KEGG: hsa:25975

STRING: 9606.ENSP00000369976

UniGene: Hs.12844

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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