EIF2A Antibody

Datasheet

Code	CSB-PA007509GA01HU
Size	$600
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Product Details
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Target Background

Product Details

Uniprot No.

Q9BY44

Target Names

EIF2A

Alternative Names

65 kDa eukaryotic translation initiation factor 2A antibody; CDA 02 antibody; CDA02 antibody; EIF 2 antibody; EIF 2A antibody; eIF-2A antibody; EIF2 antibody; eif2a antibody; EIF2A_HUMAN antibody; Eukaryotic translation initiation factor 2A 65kDa antibody; Eukaryotic translation initiation factor 2A antibody; MST089 antibody; MSTP004 antibody; MSTP089 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human EIF2A

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB,IHC,IF

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.

Gene References into Functions

Data suggest that neither eIF2A nor eIF2D are involved in the translation of this Sindbis virus subgenomic mRNA (sgmRNA) bearing non-AUG codons. PMID: 28240315
HRD1 prevents apoptosis in renal tubular epithelial cells by mediating eIF-2a ubiquitylation and degradation. PMID: 29233968
POSTN may function as a protective factor for osteoblasts during this process by inhibiting the eIF2alphaATF4 pathway. PMID: 29207036
findings indicate that MSI1 plays a leading role in stress granule formation that grants cancer stem cell properties and chemoresistant stress granules in GBM, in response to stressful conditions via the PKR/eIF2alpha signalling cascade. PMID: 29486283
There was no statistically significant difference in IFN therapeutic effectiveness among the patients with different genotypes of eIF-2a-reg2. PMID: 17407708
activation by mechanical force PMID: 15781241
FN has a role in controlling translation through beta1 integrin and eukaryotic initiation factors 4 and 2 coordinated pathways PMID: 15961545

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Protein Families

WD repeat EIF2A family

Tissue Specificity

Widely expressed. Expressed at higher level in pancreas, heart, brain and placenta.

Database Links

HGNC: 3254

OMIM: 609234

KEGG: hsa:83939

STRING: 9606.ENSP00000417229

UniGene: Hs.655782

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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