ELF2 Antibody

Datasheet

Code	CSB-PA618015DSR2HU
Size	US$166
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Image	Western blot All lanes: ELF2 antibody at 2.27μg/ml Lane 1: HL60 whole cell lysate Lane 2: A549 whole cell lysate Lane 3: MCF-7 whole cell lysate Lane 4: Jurkat whole cell lysate Lane 5: Hela whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 64, 63, 57, 58, 55 kDa Observed band size: 64, 50 kDa Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA618015DSR2HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA618015DSR2HU at dilution of 1:100
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ELF2 Polyclonal antibody

Uniprot No.

Q15723

Target Names

ELF2

Alternative Names

ELF2 antibody; NERFETS-related transcription factor Elf-2 antibody; E74-like factor 2 antibody; New ETS-related factor antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human ETS-related transcription factor Elf-2 protein (1-140AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Isoform 1 transcriptionally activates the LYN and BLK promoters and acts synergistically with RUNX1 to transactivate the BLK promoter.; Isoform 2 may function in repression of RUNX1-mediated transactivation.

Gene References into Functions

Mutations in eIF2B genes cause vanishing white matter disease due to translation defects. PMID: 29632131
Our findings collectively support a potential role of triiodothyronine and its receptor in tumor growth inhibition through regulation of ELF2 PMID: 26968954
PCAT7 contributed to the progression of nasopharyngeal carcinoma through regulating miR-134-5p/ELF2 signaling pathway. PMID: 28728844
angiopoietin-1 regulates expression of NERF2 and its own receptor in hypoxic cells. PMID: 11967990
NERF/ELF-2 physically interacts with AML1 and mediates opposing effects on AML1-mediated transcription of the B cell-specific blk gene PMID: 14970218
These findings indicate that ELF2/NERF promotes VCP transcription and that ELF2/NERF-VCP pathway might be important for cell survival and proliferation under cytokine stress. PMID: 17368566
ELF2 transactivates VCP promoter through binding to two motifs, with a predominant contribution of the upstream one. PMID: 18544453
Affinity of the CAL PDZ domain for the cystic fibrosis transmembrane conductance regulator (CFTR) C-terminus is much weaker than that of the NHERF1/NHERF2 domains, enabling wild-type CFTR to avoid premature entrapment in the lysosomal pathway. PMID: 18754678

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Subcellular Location

Nucleus.

Protein Families

ETS family

Tissue Specificity

Expressed in all fetal and adult tissues examined. Among fetal tissues, highest levels of expression detected in heart, lung, liver and kidney, and lower levels in brain. Among adult tissues, highest levels of expression detected in heart, placenta, lung,

Database Links

HGNC: 3317

KEGG: hsa:1998

STRING: 9606.ENSP00000265495

UniGene: Hs.634040

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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