EMCN Antibody

Code CSB-PA007632ESR1HU
Size US$167Purchase it in Cusabio online store
(only available for customers from the US)
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  • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA007632ESR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA007632ESR1HU at dilution of 1:100

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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) EMCN Polyclonal antibody
Uniprot No. Q9ULC0
Target Names EMCN
Alternative Names EMCN antibody; EMCN2 antibody; Endomucin 2 antibody; Endomucin antibody; Endomucin-2 antibody; Endothelial sialomucin antibody; Gastric cancer antigen Ga34 antibody; MUC-14 antibody; MUC14 antibody; MUCEN_HUMAN antibody; Mucin 14 antibody; Mucin-14 antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Endomucin protein (19-135AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Antigen Affinity Purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form Liquid
Tested Applications ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Target Data

Function Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix.
Gene References into Functions
  1. In contrast, endomucin (EMCN) is present on the lymphatic sinus endothelium and not on lymphatic endothelium of the subcapsular sinus. Moreover, both murine and human MSR1 on lymphatic endothelium of the SS bind lymphocytes and in in vivo studies MSR1 regulates entrance of lymphocytes from the SS to the lymph node parenchyma PMID: 27601677
  2. These results indicate that endomucin prevents leukocyte contact with adhesion molecules in non-inflamed tissues and that downregulation of endomucin is critical to facilitate adhesion of leukocytes into inflamed tissues. PMID: 26831939
  3. Knockdown of endomucin markedly attenuated endothelial cell growth, migration and tube formation. PMID: 21666600
  4. A significant association between EMCN and rheumatoid arthritis susceptibility was detected in our Japanese study population. The EMCN allele conferring rheumatoid arthritis susceptibility may also contribute to the pathogenesis of rheumatoid arthritis. PMID: 21159824
Subcellular Location Isoform 1: Cell membrane, Single-pass type I membrane protein, Membrane, Single-pass type I membrane protein
Tissue Specificity Expressed in heart, kidney and lung.
Database Links

HGNC: 16041

OMIM: 608350

KEGG: hsa:51705

STRING: 9606.ENSP00000296420

UniGene: Hs.152913

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