ESAM Antibody

Code CSB-PA007818GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
ESAM
Alternative Names
2310008D05Rik antibody; Endothelial cell adhesion molecule antibody; Endothelial cell selective adhesion molecule antibody; Endothelial cell-selective adhesion molecule antibody; Esam antibody; ESAM_HUMAN antibody; HUEL (C4orf1) interacting protein antibody; LP4791 protein antibody; W117m antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human ESAM
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Can mediate aggregation most likely through a homophilic molecular interaction.
Gene References into Functions
  1. sESAM levels associate with myocardial infarction, heart failure, and death after adjustment for demographic and clinical risk factors, but not after adjustment for kidney function. PMID: 26523992
  2. ESAM is a novel human hematopoietic stem cell marker associated with a subset of human leukemias PMID: 26774386
  3. Serum ESAM is higher in type 2 diabetes mellitus than in controls and parallels oxidative stress. PMID: 24456423
  4. sESAM is associated with albuminuria and reduced kidney function in patients with coronary artery disease in both cross-sectional and longitudinal analyses. PMID: 24177327
  5. ESAM regulates tumor metastasis through endothelial cell migration and tube formation in metastatic nodules. PMID: 20153339
  6. sESAM is a predictive biomarker and potential mediator of atherosclerosis. PMID: 19759376

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Subcellular Location
Cell junction, adherens junction. Cell junction, tight junction. Cell membrane; Single-pass type I membrane protein.
Tissue Specificity
Highly expressed in endothelial cells.
Database Links

HGNC: 17474

OMIM: 614281

KEGG: hsa:90952

STRING: 9606.ENSP00000278927

UniGene: Hs.173840

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