ESAM Antibody

Datasheet

Code	CSB-PA850258LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA850258LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ESAM Polyclonal antibody

Uniprot No.

Q96AP7

Target Names

ESAM

Alternative Names

2310008D05Rik antibody; Endothelial cell adhesion molecule antibody; Endothelial cell selective adhesion molecule antibody; Endothelial cell-selective adhesion molecule antibody; Esam antibody; ESAM_HUMAN antibody; HUEL (C4orf1) interacting protein antibody; LP4791 protein antibody; W117m antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Endothelial cell-selective adhesion molecule protein (30-248AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The ESAM Antibody (Product code: CSB-PA850258LA01HU) is Non-conjugated. For ESAM Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA850258LB01HU	ESAM Antibody, HRP conjugated	ELISA
FITC	CSB-PA850258LC01HU	ESAM Antibody, FITC conjugated
Biotin	CSB-PA850258LD01HU	ESAM Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Can mediate aggregation most likely through a homophilic molecular interaction.

Gene References into Functions

sESAM levels associate with myocardial infarction, heart failure, and death after adjustment for demographic and clinical risk factors, but not after adjustment for kidney function. PMID: 26523992
ESAM is a novel human hematopoietic stem cell marker associated with a subset of human leukemias PMID: 26774386
Serum ESAM is higher in type 2 diabetes mellitus than in controls and parallels oxidative stress. PMID: 24456423
sESAM is associated with albuminuria and reduced kidney function in patients with coronary artery disease in both cross-sectional and longitudinal analyses. PMID: 24177327
ESAM regulates tumor metastasis through endothelial cell migration and tube formation in metastatic nodules. PMID: 20153339
sESAM is a predictive biomarker and potential mediator of atherosclerosis. PMID: 19759376

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Subcellular Location

Cell junction, adherens junction. Cell junction, tight junction. Cell membrane; Single-pass type I membrane protein.

Tissue Specificity

Highly expressed in endothelial cells.

Database Links

HGNC: 17474

OMIM: 614281

KEGG: hsa:90952

STRING: 9606.ENSP00000278927

UniGene: Hs.173840

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Service

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Leukocyte transendothelial migration

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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