FADS1 Antibody

Datasheet
Code CSB-PA007959GA01HU
Product Type Purified Rabbit Anti human PolyClonal Antibody
Size US$685
Uniprot No. O60427
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunogen Human FADS1
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Tested Applications ELISA,WB,IHC
Storage Buffer PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method Antigen Affinity Purified
Isotype IgG
Alias fatty acid desaturase 1;FADS1;D5D;FADS6;FADSD5;FLJ38956;FLJ90273;LLCDL1;TU12 ;
Immunogen Species Homo sapiens (Human)
Target Names FADS1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Details This protein is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.
HGNC 3574
RGD 621678
MGI 1923517
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Function Isoform 2 does not exhibit any catalytic activity toward 20
Subcellular Location Isoform 1: Endoplasmic reticulum membrane, Multi-pass membrane protein, Mitochondrion, SUBCELLULAR LOCATION: Isoform 2: Endoplasmic reticulum membrane, Multi-pass membrane protein
Protein Families Fatty acid desaturase type 1 family
Tissue Specificity Widely expressed, with highest levels in liver, brain, adrenal gland and heart. Highly expressed in fetal liver and brain.
Database Links

HGNC: 3574

OMIM: 606148

KEGG: hsa:3992

STRING: 9606.ENSP00000322229

UniGene: Hs.503546

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