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FASTKD1 Antibody

Datasheet
Code CSB-PA439656
Size US$297
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  • Western blot analysis of extracts from COS-7 cells, using FAKD1 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) FASTKD1 Polyclonal antibody
Uniprot No.
Q53R41
Target Names
FASTKD1
Alternative Names
FAKD1_HUMAN antibody; FAST kinase domain containing protein 1 antibody; FAST kinase domain-containing protein 1 antibody; FAST kinase domains 1 antibody; FASTKD1 antibody; FLJ21901 antibody; KIAA1800 antibody; OTTHUMP00000207008 antibody; OTTHUMP00000207010 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthesized peptide derived from internal of Human FAKD1.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Protocols
ELISA Protocol
Western Blotting(WB) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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FASTKD1 Antibodies

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Target Background

Function
Involved in the down-regulation of mitochondrial MT-ND3 mRNA levels which leads to decreased respiratory complex I abundance and activity.
Gene References into Functions
  1. Disruption of FASTKD1 increases ND3 mRNA level. Disrupting FASTKD1 and FASTKD4 decreases ND3 mRNA like depleting FASTKD4 alone. Each RAP domain of FASTK proteins contains a nuclease fold with a conserved aspartate residue at the putative active site. The RAP domain is essential for the function of the FASTK proteins, while the region upstream determines RNA targeting and protein localization. PMID: 28335001
Subcellular Location
Mitochondrion.
Protein Families
FAST kinase family
Tissue Specificity
Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in heart.
Database Links

HGNC: 26150

OMIM: 617529

KEGG: hsa:79675

UniGene: Hs.529276

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